Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ACLY | P53396 | 2/20 | 0.40 |
| ▸ | PPIA | P62937 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6587878 | 1.00 | LMNA (0.49) | LMNAMRGPRX4KDM4EACLYPPIA | |
| SCHEMBL6080333 | 0.90 | LMNA (0.52) | LMNAMRGPRX4KDM4EACLYPPIA | |
| SCHEMBL6080336 | 0.79 | LMNA (0.49) | LMNAMRGPRX4KDM4EACLYPPIA | |
| SCHEMBL6586308 | 0.79 | ACLY (0.40) | LMNAKDM4EACLYHPGDMEN1 | |
| SCHEMBL6586310 | 0.79 | ACLY (0.40) | LMNAKDM4EACLYHPGDMEN1 | |
| SCHEMBL6589731 | 0.76 | BRD4 (0.63) | PPIANPC1KMT2AALDH1A1 | |
| SCHEMBL6589729 | 0.76 | BRD4 (0.63) | PPIANPC1KMT2AALDH1A1 | |
| SCHEMBL6588393 | 0.76 | TDP1 (0.47) | LMNANPC1RAB9AHPGDMAPT | |
| SCHEMBL6588391 | 0.76 | TDP1 (0.47) | LMNANPC1RAB9AHPGDMAPT | |
| SCHEMBL29202172 | 0.73 | MRGPRX4 (0.52) | LMNAMRGPRX4KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | disclosed |