Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.45 |
| ▸ | NSD2 | O96028 | 2/20 | 0.44 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | EBP | Q15125 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6586342 | 0.82 | PDE4A (0.51) | SIGMAR1 | |
| SCHEMBL6582744 | 0.81 | SIGMAR1 (0.50) | SIGMAR1EBP | |
| SCHEMBL6584079 | 0.79 | PDE4B (0.43) | KMT2ASIGMAR1EBP | |
| SCHEMBL6586912 | 0.77 | PDE4B (0.46) | — | |
| SCHEMBL7369485 | 0.76 | MAPK1 (0.58) | KMT2AMAPK1HSD17B10SIGMAR1EBP | |
| SCHEMBL6584176 | 0.74 | ACHE (0.52) | SLC29A1TLR9TLR7MAPK1HSD17B10 | |
| SCHEMBL6582898 | 0.73 | PPARG (0.53) | KMT2A | |
| SCHEMBL6586702 | 0.72 | FFAR1 (0.45) | KMT2ASIGMAR1EBP | |
| SCHEMBL6583680 | 0.72 | PDE4B (0.42) | KMT2A | |
| SCHEMBL6585601 | 0.72 | PDE4B (0.42) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0928789-B1 | 6-PHENYLTETRAHYDRO-1,3-OXAZIN-2-ONE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2004-09-29 | — | — | EP | disclosed |
| US-6251897-B1 | TREATING DERMATITIS, ASTHMA | NIKKEN CHEMICALS CO., LTD (JP) | 2001-06-26 | — | — | US | disclosed |
| EP-0928789-A1 | 6-PHENYLTETRAHYDRO-1,3-OXAZIN-2-ONE DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-07-14 | — | — | EP | disclosed |