Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPME1 | Q9Y570 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 12/20 | 0.36 |
| ▸ | PARP1 | P09874 | 6/20 | 0.36 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6804341 | 0.87 | PARP1 (0.51) | DHODHPARP1 | |
| SCHEMBL6588502 | 0.82 | MET (0.41) | PARP1 | |
| SCHEMBL6804348 | 0.77 | PPME1 (0.40) | PPME1DHODHPARP1 | |
| SCHEMBL6585822 | 0.71 | PARP1 (0.40) | PARP1HPSE | |
| SCHEMBL6592104 | 0.68 | PIM1 (0.44) | PARP1HPSE | |
| SCHEMBL6589916 | 0.67 | TUBB4A (0.44) | DHODHPARP1HPSE | |
| SCHEMBL6810142 | 0.67 | PARP1 (0.53) | DHODHPARP1 | |
| SCHEMBL6578530 | 0.67 | PARP1 (0.67) | DHODHPARP1HPSE | |
| SCHEMBL6590709 | 0.66 | PKN1 (0.66) | DHODHPARP1HPSE | |
| SCHEMBL6588713 | 0.66 | HPSE (0.43) | DHODHPARP1HPSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177178-B1 | HETEROCYCLICALLY SUBSTITUTED BENZIMIDAZOLES, THE PRODUCTION AND APPLICATION THEREOF | ABBOTT GMBH & CO KG (DE) | 2004-12-29 | — | — | EP | disclosed |