Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.41 |
| ▸ | SCN2B | O60939 | 2/20 | 0.41 |
| ▸ | SCN1B | Q07699 | 2/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 3/20 | 0.37 |
| ▸ | FNTA | P49354 | 3/20 | 0.36 |
| ▸ | FNTB | P49356 | 3/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1538260 | 0.78 | FNTA (0.56) | FNTAFNTB | |
| SCHEMBL30419724 | 0.78 | FNTA (0.56) | FNTAFNTB | |
| SCHEMBL5657267 | 0.73 | FNTA (0.54) | FNTAFNTBCNR1CNR2 | |
| SCHEMBL11561833 | 0.72 | CNR1 (0.56) | CNR1CNR2 | |
| SCHEMBL7761431 | 0.72 | PTGS2 (0.54) | PTGS2POLBMAPT | |
| SCHEMBL6584469 | 0.72 | FNTA (0.72) | RORCFNTAFNTB | |
| SCHEMBL6602856 | 0.72 | FNTA (0.35) | PTGS2FNTAFNTBPGR | |
| SCHEMBL6602862 | 0.72 | FNTA (0.53) | RORCFNTAFNTB | |
| SCHEMBL6861981 | 0.72 | ALDH1A1 (0.42) | FNTAFNTBCNR1 | |
| SCHEMBL7486522 | 0.71 | SMN1; SMN2 (0.43) | FNTAFNTBCNR1CNR2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1420015-A1 | Imidazolyl derivatives | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A.S. (FR) | 2004-05-19 | — | — | EP | disclosed |
| EP-1097150-B1 | IMIDAZOLYL DERIVATIVES | CONSEILS DE RECH SET D APPLIC (FR) | 2004-03-24 | — | — | EP | disclosed |
| US-20040002531-A1 | Imidazolyl derivatives | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATION SCIENTEFIQUES, S.A.S., A FRANCE CORPORATION | 2004-01-01 | — | — | US | disclosed |
| US-6509336-B1 | Prenyl transeferase inhibitors | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES, S.A.S. (FR) | 2003-01-21 | — | — | US | disclosed |
| US-20030004342-A1 | Imidazolyl derivatives | BIOMEASURE, INC., A MASSACHUSETTS CORPORATION | 2003-01-02 | — | — | US | disclosed |
| US-6420555-B1 | IMIDAZOLE DERIVATIVES PRENYL TRANSFERASE INHIBITORS. | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES, S.A.S. (FR) | 2002-07-16 | — | — | US | disclosed |
| EP-1097150-A1 | IMIDAZOLYL DERIVATIVES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A.S. (FR) | 2001-05-09 | — | — | EP | disclosed |
| WO-1999065898-A1 | IMIDAZOLYL DERIVATIVES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES SAS (FR) | 1999-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030004342-A1 | Imidazolyl derivatives | TPI1, BCHE, CYP51A1 | SCN9A 2615/4885SCN2B 3424/4885SCN1B 3319/4885 |
| US-20040002531-A1 | Imidazolyl derivatives | TPI1, BCHE, CYP51A1 | SCN9A 2615/4885SCN2B 3424/4885SCN1B 3319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.