Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3370800 | 0.71 | — | — | |
| SCHEMBL2729711 | 0.70 | CYP1A2 (0.37) | — | |
| SCHEMBL11016288 | 0.68 | L3MBTL1 (0.43) | — | |
| SCHEMBL5248852 | 0.64 | TRPA1 (0.32) | TRPA1 | |
| SCHEMBL15075855 | 0.63 | — | — | |
| SCHEMBL30691872 | 0.63 | TRPA1 (0.58) | TRPA1 | |
| SCHEMBL9926021 | 0.63 | TRPA1 (0.58) | TRPA1 | |
| SCHEMBL29633894 | 0.63 | — | — | |
| SCHEMBL5050147 | 0.63 | TRPA1 (0.58) | TRPA1 | |
| SCHEMBL4760147 | 0.62 | TRPA1 (0.36) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1427724-A1 | NOVEL USE OF SUBSTITUTED AMINOMETHYL CHROMANS | MERCK PATENT GmbH (DE) | 2004-06-16 | — | — | EP | disclosed |
| WO-2003024960-A1 | NOVEL USE OF SUBSTITUTED AMINOMETHYL CHROMANS | MERCK PATENT GMBH (DE) | 2003-03-27 | — | — | WO | disclosed |
| US-5593979-A | TREATMENT OF AIDS WITH ENZYME INHIBITORS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1997-01-14 | — | — | US | disclosed |
| US-5593979-A | TREATMENT OF AIDS WITH ENZYME INHIBITORS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0498290-B1 | Pyridobenzodiazepines, dipyrido [3,2-b:2',3'-e] [1,4]diazepines and their use in the prevention or treatment of HIV infection | BOEHRINGER INGELHEIM PHARMA (US) | 1996-09-18 | — | — | EP | disclosed |
| EP-0498290-A1 | Pyridobenzodiazepines, dipyrido [3,2-b:2',3'-e] [1,4]diazepines and their use in the prevention or treatment of HIV infection | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1992-08-12 | — | — | EP | disclosed |
| US-4668675-A | ANTIDEPRESSANTS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1987-05-26 | — | — | US | disclosed |
| US-4556667-A | (2-((AMINOPYRIDINYL)AMINO)PHENYL)ARYLMETHANONE INTERMEDIATES | A. H. ROBINS COMPANY, INCORPORATED (US) | 1985-12-03 | — | — | US | disclosed |
| US-4495183-A | ANTIULCER AGENTS- GASTROLINTESTINAL DISORDERS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1985-01-22 | — | — | US | disclosed |
| US-4447361-A | ANTIDEPRESSANT | A. H. ROBINS COMPANY, INC. (US) | 1984-05-08 | — | — | US | disclosed |
| US-4311562-A | Method for inhibiting deposit formation in process equipment associated with separation and purification of alkyl phosphorochloridothioates | ETHYL CORPORATION (US) | 1982-01-19 | — | — | US | disclosed |
| US-4292139-A | Method for inhibiting deposit formation in distillation units associated with separation and purification of alkyl phosphorochloridothioates | ETHYL CORPORATION (US) | 1981-09-29 | — | — | US | disclosed |