Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4264647 | 0.73 | DRD2 (0.36) | TRPA1DRD2BACE1 | |
| SCHEMBL17103733 | 0.70 | TRPA1 (0.36) | TRPA1DRD2BACE1 | |
| SCHEMBL2536697 | 0.67 | TRPA1 (0.36) | TRPA1DRD2BACE1 | |
| SCHEMBL2362166 | 0.66 | DRD2 (0.35) | TRPA1DRD2BACE1 | |
| SCHEMBL3370800 | 0.66 | — | — | |
| SCHEMBL27787700 | 0.65 | TRPA1 (0.34) | TRPA1DRD2BACE1 | |
| SCHEMBL27954167 | 0.65 | TRPA1 (0.38) | TRPA1BACE1 | |
| SCHEMBL17786321 | 0.64 | MAPT (0.42) | — | |
| SCHEMBL407792 | 0.63 | DRD2 (0.33) | TRPA1DRD2BACE1 | |
| SCHEMBL2594107 | 0.63 | TRPA1 (0.33) | TRPA1BACE1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0030683-B1 | TEST COMPOSITION FOR PEROXIDATIVELY ACTIVE SUBSTANCES, TEST DEVICE CONTAINING THE COMPOSITION, PROCESS FOR PREPARING SAME AND METHOD FOR THE DETERMINATION OF PEROXIDATIVELY ACTIVE SUBSTANCES | MILES LABORATORIES, INC. (US) | 1983-04-06 | — | — | EP | claimed |
| EP-1765797-A4 | PHENOTHIAZINE DERIVATIVES AND THEIR METHOD OF USE | UNIV KANSAS CT FOR RES INC (US) | 2008-02-06 | — | — | EP | disclosed |
| EP-1765797-A1 | PHENOTHIAZINE DERIVATIVES AND THEIR METHOD OF USE | University of Kansas Center for Research, Inc. (US) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006002441-A1 | PHENOTHIAZINE DERIVATIVES AND THEIR METHOD OF USE | UNIVERSITY OF KANSAS (US) | 2006-01-05 | — | — | WO | disclosed |
| US-20050288279-A1 | Phenothiazine derivatives and their method of use | KANSAS MEDICAL CENTER, UNIVERSITY OF | 2005-12-29 | — | — | US | disclosed |
| EP-0611757-B1 | Process for the preparation of azaphenothiazines | ASTA MEDICA AG (DE) | 1999-01-20 | — | — | EP | disclosed |
| US-5539107-A | REACTION OF CHLOROPYRIDINE AND CHLOROQUINOLINES WITH MERCAPTOANILINES OR BIS/O-AMINOPHENYL DISULFIDE | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1996-07-23 | — | — | US | disclosed |
| EP-0611757-A1 | Process for the preparation of azaphenothiazines | ASTA Medica Aktiengesellschaft (DE) | 1994-08-24 | — | — | EP | disclosed |
| EP-0030683-B1 | TEST COMPOSITION FOR PEROXIDATIVELY ACTIVE SUBSTANCES, TEST DEVICE CONTAINING THE COMPOSITION, PROCESS FOR PREPARING SAME AND METHOD FOR THE DETERMINATION OF PEROXIDATIVELY ACTIVE SUBSTANCES | MILES LABORATORIES, INC. (US) | 1983-04-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288279-A1 | Phenothiazine derivatives and their method of use | SHBG, GPR119, BRDT | TRPA1 1054/4885DRD2 1423/4885BACE1 4726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.