Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.61 |
| ▸ | DRD4 | P21917 | 3/20 | 0.61 |
| ▸ | DRD3 | P35462 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6069916 | 0.78 | DRD2 (0.55) | DRD4DRD3KMT2AMAPK1DRD2 | |
| SCHEMBL6070129 | 0.78 | DRD2 (0.55) | DRD4DRD3KMT2AMAPK1DRD2 | |
| SCHEMBL24879163 | 0.76 | CHRM1 (0.51) | KDM4EDPP4HRH4ALDH1A1CHRM1 | |
| SCHEMBL6586733 | 0.74 | HTR1A (0.61) | HTR1ADRD4DRD3KDM4EKMT2A | |
| SCHEMBL6588617 | 0.74 | HTR1A (0.61) | HTR1ADRD4DRD3KDM4EKMT2A | |
| SCHEMBL6586728 | 0.73 | HTR1A (0.66) | HTR1ADRD4DRD3KDM4EKMT2A | |
| SCHEMBL27456394 | 0.72 | DPP4 (0.43) | KDM4EDPP4ALDH1A1TDP1CHRM1 | |
| SCHEMBL6586359 | 0.71 | HTR1A (0.58) | HTR1ADRD4DRD3KDM4EALDH1A1 | |
| SCHEMBL6178229 | 0.70 | MEN1 (0.55) | HTR1ADRD4KMT2AMAPK1CHRM4 | |
| SCHEMBL6070304 | 0.70 | HTR1A (0.51) | HTR1ADRD4DRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161424-B1 | NEW DIAZOLE DERIVATIVES AS SEROTONERGIC AGENTS | WYETH CORP (US) | 2004-06-02 | — | — | EP | claimed |