Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7976196 | 1.00 | CTSK (0.43) | CTSKJAK3BTKF10SMN1; SMN2 | |
| SCHEMBL1935453 | 0.77 | CTSK (0.47) | CTSKSMN1; SMN2TGM2CTSSMEN1 | |
| SCHEMBL1935450 | 0.77 | CTSK (0.47) | CTSKSMN1; SMN2TGM2CTSSMEN1 | |
| SCHEMBL13685180 | 0.77 | CTSK (0.47) | CTSKSMN1; SMN2TGM2CTSSMEN1 | |
| SCHEMBL7989630 | 0.77 | DDAH1 (0.41) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL7989626 | 0.77 | DDAH1 (0.41) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL6587122 | 0.76 | CTSS (0.51) | CTSKJAK3BTKCTSSMEN1 | |
| SCHEMBL1937079 | 0.76 | CTSK (0.46) | CTSKSMN1; SMN2TGM2CTSSMEN1 | |
| SCHEMBL3683654 | 0.76 | CTSK (0.46) | CTSKSMN1; SMN2TGM2CTSSMEN1 | |
| SCHEMBL330004 | 0.76 | CTSK (0.46) | CTSKSMN1; SMN2TGM2CTSSMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040198-A2 | MACROCYCLIC HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-06-07 | — | — | WO | disclosed |