Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | APP | P05067 | 4/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6587553 | 1.00 | POLB (0.45) | POLBGAAKDRMAPTAPP | |
| SCHEMBL6157314 | 0.83 | ALDH1A1 (0.54) | POLBKDRMAPTFFAR1KDM4E | |
| SCHEMBL6583241 | 0.82 | TRPA1 (0.48) | POLBKDRMAPTAPPFFAR1 | |
| SCHEMBL6583243 | 0.82 | TRPA1 (0.48) | POLBKDRMAPTAPPFFAR1 | |
| SCHEMBL6583468 | 0.81 | MAPT (0.47) | POLBKDRMAPTAPPFFAR1 | |
| SCHEMBL6583466 | 0.81 | MAPT (0.47) | POLBKDRMAPTAPPFFAR1 | |
| SCHEMBL6583665 | 0.80 | KDR (0.49) | POLBGAAKDRMAPTAPP | |
| SCHEMBL6583671 | 0.80 | KDR (0.49) | POLBGAAKDRMAPTAPP | |
| SCHEMBL6587340 | 0.79 | MAPT (0.49) | POLBKDRMAPTAPPFFAR1 | |
| SCHEMBL6587331 | 0.79 | MAPT (0.49) | POLBKDRMAPTAPPFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710659-B1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-01-28 | — | — | EP | disclosed |
| EP-0710659-A1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |