SCHEMBL172934

SCHEMBL172934

CC1Nc2ccccc2C1C

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTR5A P47898 8/20 0.41
CREBBP Q92793 3/20 0.38
BRPF1 P55201 1/20 0.38
IDO1 P14902 1/20 0.36
NOS2 P35228 1/20 0.35
PBRM1 Q86U86 1/20 0.35
TNKS2 Q9H2K2 1/20 0.35
BRD4 O60885 3/20 0.34
EP300 Q09472 1/20 0.34
ABCB1 P08183 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
HTT P42858 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18324162 1.00 HTR5A (0.41) HTR5ACREBBPBRPF1IDO1NOS2
SCHEMBL18324164 1.00 HTR5A (0.41) HTR5ACREBBPBRPF1IDO1NOS2
SCHEMBL29501187 1.00 HTR5A (0.41) HTR5ACREBBPBRPF1IDO1NOS2
SCHEMBL7571631 1.00 HTR5A (0.41) HTR5ACREBBPBRPF1IDO1NOS2
SCHEMBL19308765 1.00 HTR5A (0.41) HTR5ACREBBPBRPF1IDO1NOS2
SCHEMBL7571638 1.00 HTR5A (0.41) HTR5ACREBBPBRPF1IDO1NOS2
SCHEMBL18269674 1.00 HTR5A (0.41) HTR5ACREBBPBRPF1IDO1NOS2
SCHEMBL18271939 1.00 HTR5A (0.41) HTR5ACREBBPBRPF1IDO1NOS2
SCHEMBL3626533 0.77 HTR5A (0.39) HTR5ACREBBPBRPF1IDO1NOS2
SCHEMBL28473294 0.77 HTR5A (0.39) HTR5ACREBBPBRPF1NOS2PBRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-63264567-A None JP disclosed
EP-4123735-B1 ORGANOELECTROLUMINESCENT DEVICE USING POLYCYCLIC AROMATIC COMPOUNDS SFC CO LTD (KR) 2026-04-01 EP disclosed
US-12543493-B2 Organic light-emitting device SFC CO., LTD. (KR) 2026-02-03 US disclosed
EP-3885350-B1 NOVEL BORON COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME SFC CO LTD (KR) 2025-09-03 EP disclosed
US-20250171420-A1 MOLECULAR GLUE DEGRADERS AND METHODS OF USING THE SAME MONTE ROSA THERAPEUTICS AG (CH) 2025-05-29 US disclosed
US-12291543-B2 Boron compound and organic light-emitting diode comprising same SFC CO., LTD. (KR) 2025-05-06 US disclosed
EP-4540240-A1 MOLECULAR GLUE DEGRADERS AND METHODS OF USING THE SAME Monte Rosa Therapeutics AG (CH) 2025-04-23 EP disclosed
US-20240196736-A1 ORGANIC LIGHT-EMITTING DEVICE SFC CO., LTD. (KR) 2024-06-13 US disclosed
EP-4300608-A1 ORGANIC LIGHT-EMITTING DEVICE SFC Co., Ltd. (KR) 2024-01-03 EP disclosed
WO-2023244815-A1 MOLECULAR GLUE DEGRADERS AND METHODS OF USING THE SAME MONTE ROSA THERAPEUTICS, INC. (US) 2023-12-21 WO disclosed
EP-0363466-A1 NOVEL COMPOUNDS BEECHAM GROUP PLC (GB) 1990-04-18 EP disclosed
WO-1989009217-A1 NOVEL COMPOUNDS BEECHAM GROUP PLC (GB) 1989-10-05 WO disclosed
US-4871744-A TREATMENT OF ANXIETY, PSYCHOSIS, MIGRAINS BEECHAM GROUP P.L.C. (GB) 1989-10-03 US disclosed
JP-S63264567-A PRODUCTION OF 2,3-DIMETHYLINDOLINE KAWAKEN FINE CHEM CO LTD 1988-11-01 JP disclosed
US-4741981-A Photosensitive material for electrophotography contains organic phosphite compounds RICOH CO., LTD. (JP) 1988-05-03 US disclosed
US-4661428-A HIGH ENERGY DENSITY; LIGHTWEIGHT SUBSTRATES RICOH CO., LTD. (JP) 1987-04-28 US disclosed
US-4521504-A DICHROMATIC IMAGES-CONDUCTIVE SUBSTRATE LAMINATED WITH PHOTOCONDUCTIVE RICOH COMPANY, LTD. (JP) 1985-06-04 US disclosed
US-4370398-A Electrostatic copying process RICOH COMPANY, LTD. (JP) 1983-01-25 US disclosed
US-4361638-A AMORPHOUS SILICON AND CARBON BASE MATERIAL DOPED WITH HYDROGEN AND FLUORINE FUJI PHOTO FILM CO., LTD. (JP) 1982-11-30 US disclosed
US-4089853-A Process for the preparation of cis-5,6-dimethoxy-2-methyl-3-[2-(4-phenyl-1-piperazinyl)-ethyl]indoline AMERICAN CYANAMID COMPANY (US) 1978-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12543493-B2 Organic light-emitting device CRY1, CRY2, AOC2 HTR5A 1635/4885CREBBP 4364/4885BRPF1 2360/4885
US-20240196736-A1 ORGANIC LIGHT-EMITTING DEVICE AOX1, CRY2, SUN2 HTR5A 2059/4885CREBBP 3107/4885BRPF1 262/4885
US-20250171420-A1 MOLECULAR GLUE DEGRADERS AND METHODS OF USING THE SAME PSMA1, CSNK1G1, CSNK1A1 HTR5A 4206/4885CREBBP 2136/4885BRPF1 2325/4885
US-12291543-B2 Boron compound and organic light-emitting diode comprising same CLTB, CD79B, CYBA HTR5A 4284/4885CREBBP 4229/4885BRPF1 86/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.