Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23148487 | 0.76 | MAPT (0.61) | HTTSMN1; SMN2PKMLMNAMAPK1 | |
| SCHEMBL5189520 | 0.71 | SMN1; SMN2 (0.59) | HTTSMN1; SMN2PKMLMNAMAPK1 | |
| SCHEMBL28051137 | 0.71 | HTT (0.61) | HTTSMN1; SMN2PKMLMNAMAPT | |
| SCHEMBL6340701 | 0.70 | SMN1; SMN2 (0.49) | HTTSMN1; SMN2PKMLMNAMAPK1 | |
| SCHEMBL6340645 | 0.70 | TUBB4A (0.56) | HTTSMN1; SMN2PKMLMNAMAPK1 | |
| SCHEMBL6073370 | 0.70 | CA12 (0.59) | HTTSMN1; SMN2PKMLMNAMAPK1 | |
| SCHEMBL16862848 | 0.70 | RORC (0.82) | HTTSMN1; SMN2PKMLMNAMAPT | |
| SCHEMBL12614628 | 0.70 | NR4A2 (0.55) | SMN1; SMN2LMNAMAPTMEN1KMT2A | |
| SCHEMBL6343982 | 0.68 | SMN1; SMN2 (0.60) | HTTSMN1; SMN2PKMLMNAMAPK1 | |
| SCHEMBL6342356 | 0.68 | HTT (0.46) | HTTSMN1; SMN2PKMLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181269-B1 | CELL PROLIFERATION INHIBITORS | ABBOTT LAB (US) | 2004-02-25 | — | — | EP | claimed |