Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6588931 | 1.00 | HSP90AA1 (0.34) | HSP90AA1PTGDR2 | |
| Trifluoroacetic Acid SCHEMBL6584844 | 0.89 | CAMK2D (0.37) | HSP90AA1PTGDR2 | |
| Trifluoroacetic Acid SCHEMBL6587804 | 0.84 | ACLY (0.34) | HSP90AA1 | |
| Trifluoroacetic Acid SCHEMBL6587800 | 0.84 | ACLY (0.34) | HSP90AA1 | |
| SCHEMBL6588558 | 0.83 | ICMT (0.39) | HSP90AA1 | |
| Trifluoroacetic Acid SCHEMBL6585782 | 0.81 | CAMK2D (0.45) | HSP90AA1PTGDR2 | |
| SCHEMBL6588554 | 0.81 | GSK3B (0.34) | HSP90AA1 | |
| Trifluoroacetic Acid SCHEMBL6591980 | 0.80 | ICMT (0.37) | HSP90AA1PTGDR2 | |
| SCHEMBL27581115 | 0.80 | HSP90AA1 (0.37) | HSP90AA1 | |
| Trifluoroacetic Acid SCHEMBL6588330 | 0.80 | CAMK2D (0.43) | HSP90AA1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183252-B1 | PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-18 | — | — | EP | disclosed |
| EP-1183252-A1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | AstraZeneca AB (SE) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000071537-A1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRAZENECA AB (SE) | 2000-11-30 | — | — | WO | disclosed |