Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TIPARP | Q7Z3E1 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL6589272 | 0.87 | GAA (0.45) | EEDCA12CA1CA2CA9 | |
| Fumaric Acid SCHEMBL6589279 | 0.87 | GAA (0.45) | EEDCA12CA1CA2CA9 | |
| SCHEMBL7611671 | 0.77 | ALDH1A1 (0.57) | ALDH1A1HPGDSMN1; SMN2KDM4EMAPT | |
| SCHEMBL28179036 | 0.76 | LATS1 (0.51) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL20755156 | 0.74 | LATS1 (0.54) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL29546679 | 0.73 | NPC1 (0.55) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL20521379 | 0.71 | ADRB2 (0.52) | CA12CA1CA2CA9 | |
| SCHEMBL7480165 | 0.71 | TGFBR1 (0.35) | EEDHPGDMAPTLOXL2 | |
| SCHEMBL5715607 | 0.70 | TAS1R3 (0.50) | ALDH1A1HPGDSMN1; SMN2TDP1MAPT | |
| Hydrochloric Acid SCHEMBL29586065 | 0.70 | ADRB2 (0.50) | CA12CA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0703232-B1 | 2,3-Dihydro-1H-isoindole derivates, a process for their preparation and their use as serotonin reuptake inhibitors | AVENTIS PHARMA INC (US) | 2004-06-30 | — | — | EP | claimed |