Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6589247 | 1.00 | CRHBP (0.36) | CRHBPCRHR2AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL6592470 | 0.91 | LMNA (0.39) | AKR1C3AKR1C2AKR1C1ALDH1A1LMNA | |
| SCHEMBL6592477 | 0.91 | LMNA (0.39) | AKR1C3AKR1C2AKR1C1ALDH1A1LMNA | |
| SCHEMBL6589192 | 0.84 | ALDH1A1 (0.35) | ALDH1A1LMNACYP3A4CYP1A2CYP2C9 | |
| SCHEMBL6589188 | 0.84 | ALDH1A1 (0.35) | ALDH1A1LMNACYP3A4CYP1A2CYP2C9 | |
| SCHEMBL6590655 | 0.81 | ALDH1A1 (0.40) | ALDH1A1LMNACYP3A4CYP1A2CYP2C9 | |
| SCHEMBL6590663 | 0.81 | ALDH1A1 (0.40) | ALDH1A1LMNACYP3A4CYP1A2CYP2C9 | |
| SCHEMBL6592593 | 0.79 | ALDH1A1 (0.33) | ALDH1A1LMNACYP3A4CYP1A2CYP2C9 | |
| SCHEMBL6592597 | 0.79 | ALDH1A1 (0.33) | ALDH1A1LMNACYP3A4CYP1A2CYP2C9 | |
| SCHEMBL6589257 | 0.76 | IGF1R (0.35) | ALDH1A1CYP1A2CYP2C9CYP2C19HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1414887-A1 | METHOD OF POLYCARBONATE PREPARATION | GENERAL ELECTRIC COMPANY (US) | 2004-05-06 | — | — | EP | disclosed |
| WO-2003010218-A1 | METHOD OF POLYCARBONATE PREPARATION | GENERAL ELECTRIC COMPANY (US) | 2003-02-06 | — | — | WO | disclosed |