SCHEMBL6590663

SCHEMBL6590663

CC1CC(c2ccc(O)c(-c3ccccc3)c2)CC(C)(C)C1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.40
LMNA P02545 2/20 0.40
CYP3A4 P08684 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
BACE1 P56817 2/20 0.39
NR1I2 O75469 1/20 0.36
ABCB11 O95342 1/20 0.36
KDM1A O60341 3/20 0.35
HPGD P15428 1/20 0.34
BCL2L1 Q07817 1/20 0.34
HSD17B10 Q99714 1/20 0.34
MAOA P21397 2/20 0.34
PELI1 Q96FA3 1/20 0.34
MAOB P27338 1/20 0.34
GAA P10253 3/20 0.34
KDM4E B2RXH2 2/20 0.34
POLB P06746 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6590655 1.00 ALDH1A1 (0.40) ALDH1A1LMNACYP3A4CYP1A2CYP2C9
SCHEMBL6592470 0.86 LMNA (0.39) ALDH1A1LMNACYP3A4CYP1A2CYP2C9
SCHEMBL6592477 0.86 LMNA (0.39) ALDH1A1LMNACYP3A4CYP1A2CYP2C9
SCHEMBL6589244 0.81 CRHBP (0.36) ALDH1A1LMNACYP3A4CYP1A2CYP2C9
SCHEMBL6589247 0.81 CRHBP (0.36) ALDH1A1LMNACYP3A4CYP1A2CYP2C9
SCHEMBL7119393 0.79 ESR1 (0.43) ALDH1A1LMNACYP3A4CYP1A2CYP2C9
SCHEMBL5452463 0.78 ACMSD (0.56) ALDH1A1LMNACYP3A4CYP1A2CYP2C9
SCHEMBL27675569 0.78 OPRM1 (0.36) ALDH1A1LMNACYP3A4ALOX5
SCHEMBL4126596 0.78 ALDH1A1 (0.37) ALDH1A1LMNACYP3A4CYP1A2CYP2C9
SCHEMBL19031705 0.78 LMNA (0.37) ALDH1A1LMNACYP3A4CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113166500-A Polyethylene with additives for increasing environmental stress crack resistance SABIC环球技术有限责任公司 2021-07-23 CN disclosed
CN-108463481-B Method for producing polycarbonate 国际壳牌研究有限公司 2021-04-09 CN disclosed
CN-108291014-B Polyarylate resin, process for producing the same, and polyarylate resin composition 尤尼吉可株式会社 2021-03-19 CN disclosed
CN-105837801-B Polyarylate resin solution composition, process for producing polyarylate resin film, three-layer film, laminated plate, and printed circuit board 住友化学株式会社 2021-03-02 CN disclosed
CN-112384489-A Method for producing organic compound 尤尼吉可株式会社 2021-02-19 CN disclosed
CN-112313277-A Polyethylene with polycarbonate-siloxane for improved environmental stress crack resistance SABIC环球技术有限责任公司 2021-02-02 CN disclosed
CN-108473672-B Process for preparing melt polycarbonate 国际壳牌研究有限公司 2020-12-08 CN disclosed
CN-111868612-A Polycarbonate having electro-optical effect, method for producing same, and light control element using same 帝人株式会社 2020-10-30 CN disclosed
US-10654973-B2 Method for producing polycarbonate SHELL OIL COMPANY (US) 2020-05-19 US disclosed
US-10640609-B2 Method for preparing a melt polycarbonate SHELL OIL COMPANY (US) 2020-05-05 US disclosed
CN-101331169-A Equipment cleaning in polycarbonate manufacture GEN ELECTRIC (US) 2008-12-24 CN disclosed
CN-101056913-A Process to make polycarbonate from bismethylsalicylcarbonate (BMSC) GEN ELECTRIC (US) 2007-10-17 CN disclosed
CN-1972982-A Method for preparing a polycarbonate oligomer mixture at low temperature for manufacturing polycarbonate GEN ELECTRIC (US) 2007-05-30 CN disclosed
CN-1914248-A Process for the production of copolycarbonates with reduced color GEN ELECTRIC (US) 2007-02-14 CN disclosed
CN-1694914-A Method and apparatus for preparing high molecular weight melt polycarbonate GEN ELECTRIC (US) 2005-11-09 CN disclosed
EP-1414888-A1 EXTRUSION METHOD FOR MAKING POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2004-05-06 EP disclosed
EP-1414887-A1 METHOD OF POLYCARBONATE PREPARATION GENERAL ELECTRIC COMPANY (US) 2004-05-06 EP disclosed
WO-2003010220-A1 EXTRUSION METHOD FOR MAKING POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2003-02-06 WO disclosed
WO-2003010218-A1 METHOD OF POLYCARBONATE PREPARATION GENERAL ELECTRIC COMPANY (US) 2003-02-06 WO disclosed
CN-1383450-A Antibody molecule with specificity to human tumor necrosis factor alpha and application thereof CELLTECH R&D LTD (GB) 2002-12-04 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10640609-B2 Method for preparing a melt polycarbonate PKD1, HSD17B7, DHCR7 ALDH1A1 4008/4885LMNA 1563/4885CYP3A4 460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.