Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | HMOX2 | P30519 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20954611 | 0.93 | ALDH1A1 (0.48) | MAOBKDM4EALDH1A1LMNARAB9A | |
| SCHEMBL29371114 | 0.93 | ALDH1A1 (0.48) | MAOBKDM4EALDH1A1LMNARAB9A | |
| SCHEMBL23461686 | 0.85 | MAPK1 (0.49) | MAOBALDH1A1LMNARAB9AL3MBTL1 | |
| SCHEMBL34466222 | 0.81 | SMYD2 (0.34) | KDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL6585325 | 0.81 | ENPP2 (0.43) | KDM4ELMNAL3MBTL1HTTKMT2A | |
| SCHEMBL1284441 | 0.80 | RAB9A (0.48) | MAOBKDM4EALDH1A1LMNARAB9A | |
| SCHEMBL4470099 | 0.80 | MAOB (0.42) | MAOBKDM4EALDH1A1LMNARAB9A | |
| SCHEMBL29910455 | 0.80 | MAOB (0.42) | MAOBKDM4EALDH1A1LMNARAB9A | |
| SCHEMBL6651489 | 0.80 | TAAR1 (0.42) | MAOB | |
| SCHEMBL10801659 | 0.77 | MAOB (0.67) | MAOBKDM4EALDH1A1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036062-B1 | HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE (MMP) INHIBITORS | PFIZER LTD (GB) | 2004-01-02 | — | — | EP | disclosed |
| US-6495568-B1 | TREATMENT OF TISSUE ULCERATION, WOUND REPAIR AND SKIN DISEASES | WARNER-LAMBERT COMPANY | 2002-12-17 | — | — | US | disclosed |