Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7411094 | 0.90 | LTA4H (0.36) | ENPP2LMNAL3MBTL1MAPK1PPARA | |
| SCHEMBL23461686 | 0.82 | MAPK1 (0.49) | LMNAL3MBTL1MAPK1POLBKMT2A | |
| SCHEMBL6589309 | 0.81 | MAOB (0.47) | LMNAL3MBTL1KDM4EHTTKMT2A | |
| SCHEMBL29371114 | 0.74 | ALDH1A1 (0.48) | LMNAL3MBTL1KDM4EHTTKMT2A | |
| SCHEMBL20954611 | 0.74 | ALDH1A1 (0.48) | LMNAL3MBTL1KDM4EHTTKMT2A | |
| SCHEMBL3289227 | 0.74 | ENPP2 (0.54) | ENPP2LMNAL3MBTL1MGLLKDM4E | |
| SCHEMBL12075598 | 0.74 | LPL (0.42) | MGLLPPARGCA1CA2 | |
| SCHEMBL6586842 | 0.73 | ENPP2 (0.62) | ENPP2MAPK1KDM4ECA1CA2 | |
| SCHEMBL4508412 | 0.73 | ENPP2 (0.56) | ENPP2LMNAMAPK1MGLLKDM4E | |
| SCHEMBL7630706 | 0.73 | PKM (0.60) | LMNAL3MBTL1MAPK1PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036062-B1 | HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE (MMP) INHIBITORS | PFIZER LTD (GB) | 2004-01-02 | — | — | EP | disclosed |
| US-6495568-B1 | TREATMENT OF TISSUE ULCERATION, WOUND REPAIR AND SKIN DISEASES | WARNER-LAMBERT COMPANY | 2002-12-17 | — | — | US | disclosed |