Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.35 |
| ▸ | ESRRA | P11474 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | FASN | P49327 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.33 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6832170 | 0.74 | ELANE (0.36) | ARCYP11B2ESRRAELANEVCAM1 | |
| SCHEMBL7142077 | 0.73 | GRIN2D (0.35) | KMT2APGR | |
| SCHEMBL5231465 | 0.73 | SLC9A1 (0.41) | CACNA1BKMT2AIDO1 | |
| SCHEMBL6832132 | 0.69 | ALK (0.34) | CYP11B2ESRRALMNAIDO1ABCC9 | |
| SCHEMBL6211150 | 0.68 | PGR (0.52) | PGR | |
| SCHEMBL7102762 | 0.68 | PGR (0.40) | KMT2APGR | |
| SCHEMBL3187330 | 0.66 | CYP11B2 (0.40) | ARCYP11B2ELANEFASNVCAM1 | |
| SCHEMBL11027190 | 0.65 | ALDH1A1 (0.39) | KMT2AIDO1 | |
| SCHEMBL11825218 | 0.64 | TP53 (0.54) | ARCYP11B2ELANEFASNIDO1 | |
| SCHEMBL77027 | 0.63 | CYP3A4 (0.50) | ARCYP3A4IDO1VCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0809629-B1 | 2-PHENYL-SUBSTITUTED HETEROCYCLIC 1,3-KETONOLS AS HERBICIDES AND PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2004-06-30 | — | — | EP | disclosed |
| US-6746990-B2 | INSECTICIDES, ACARICIDES AND HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2004-06-08 | — | — | US | disclosed |
| US-20030045432-A1 | Phenyl-substituted cyclic ketoenols | FISCHER REINER (DE) | 2003-03-06 | — | — | US | disclosed |
| US-6358887-B1 | PREEMERGENCE, POSTEMERGENCE HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-03-19 | — | — | US | disclosed |
| EP-0809629-A1 | 2-PHENYL-SUBSTITUTED HETEROCYCLIC 1,3-KETONOLS AS HERBICIDES AND PESTICIDES | BAYER AG (DE) | 1997-12-03 | — | — | EP | disclosed |
| WO-1996025395-A1 | 2-PHENYL-SUBSTITUTED HETEROCYCLIC 1,3-KETONOLS AS HERBICIDES AND PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-08-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030045432-A1 | Phenyl-substituted cyclic ketoenols | CYP19A1, DDT, CYP8B1 | AR 1439/4885CYP11B2 28/4885ESRRA 244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.