Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3863103 | 0.81 | SLC5A1 (0.37) | PTGS2 | |
| SCHEMBL4959110 | 0.75 | PTGS2 (0.48) | PTGS2PTGS1 | |
| SCHEMBL3863109 | 0.70 | BRD4 (0.34) | — | |
| SCHEMBL4958867 | 0.70 | PTGS2 (0.46) | PTGS2PTGS1 | |
| SCHEMBL6590005 | 0.69 | PTGS2 (0.43) | PTGS2PTGS1 | |
| SCHEMBL28319223 | 0.68 | PDE4A (0.50) | — | |
| SCHEMBL9024857 | 0.68 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL3864654 | 0.67 | PTGS2 (0.57) | PTGS2PTGS1 | |
| SCHEMBL8758585 | 0.67 | PTGS2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL16770523 | 0.67 | CA12 (0.58) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246621-A4 | NITROSATED AND NITROSYLATED CYCLOOXYGENASE-2 INHIBITORS, COMPOSITIONS AND METHODS OF USE | NITROMED INC (US) | 2004-11-24 | — | — | EP | claimed |
| EP-1246621-A1 | NITROSATED AND NITROSYLATED CYCLOOXYGENASE-2 INHIBITORS, COMPOSITIONS AND METHODS OF USE | Nitromed, Inc. (US) | 2002-10-09 | — | — | EP | claimed |
| WO-2001045703-A1 | NITROSATED AND NITROSYLATED CYCLOOXYGENASE-2 INHIBITORS, COMPOSITIONS AND METHODS OF USE | NITROMED, INC. (US) | 2001-06-28 | — | — | WO | claimed |
| EP-1246621-A4 | NITROSATED AND NITROSYLATED CYCLOOXYGENASE-2 INHIBITORS, COMPOSITIONS AND METHODS OF USE | NITROMED INC (US) | 2004-11-24 | — | — | EP | disclosed |
| EP-1246621-A1 | NITROSATED AND NITROSYLATED CYCLOOXYGENASE-2 INHIBITORS, COMPOSITIONS AND METHODS OF USE | Nitromed, Inc. (US) | 2002-10-09 | — | — | EP | disclosed |
| WO-2001045703-A1 | NITROSATED AND NITROSYLATED CYCLOOXYGENASE-2 INHIBITORS, COMPOSITIONS AND METHODS OF USE | NITROMED, INC. (US) | 2001-06-28 | — | — | WO | disclosed |