⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL177598 | 0.83 | CXCR3 (0.33) | — | |
| SCHEMBL7409277 | 0.81 | — | — | |
| SCHEMBL6247796 | 0.75 | — | — | |
| SCHEMBL4461735 | 0.69 | ALDH1A1 (0.33) | — | |
| SCHEMBL73136 | 0.69 | — | — | |
| SCHEMBL316395 | 0.66 | — | — | |
| SCHEMBL11700246 | 0.64 | PIN1 (0.35) | — | |
| SCHEMBL2687390 | 0.64 | PIN1 (0.35) | — | |
| SCHEMBL6158731 | 0.64 | — | — | |
| SCHEMBL1053003 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024121253-A1 | NOVEL N,N-DIMETHYLTRYPTAMINE (DMT) DERIVATIVES AND USES THEREOF | MIHKAL GMBH (CH) | 2024-06-13 | — | — | WO | disclosed |
| US-11845759-B2 | Opioid compounds and uses thereof | RHODES TECHNOLOGIES (US) | 2023-12-19 | — | — | US | disclosed |
| US-20210061815-A1 | NOVEL OPIOID COMPOUNDS AND USES THEREOF | RHODES TECHNOLOGIES (US) | 2021-03-04 | — | — | US | disclosed |
| EP-3755704-A1 | NOVEL OPIOID COMPOUNDS AND USES THEREOF | Rhodes Technologies Inc. (US) | 2020-12-30 | — | — | EP | disclosed |
| US-10435406-B2 | 6,7-cyclicmorphinan derivatives and use thereof | PURDUE PHARMA L.P. (US) | 2019-10-08 | — | — | US | disclosed |
| WO-2019165298-A1 | NOVEL OPIOID COMPOUNDS AND USES THEREOF | RHODES TECHNOLOGIES (US) | 2019-08-29 | — | — | WO | disclosed |
| EP-2941433-B1 | PROCESS FOR PREPARING 7 -SUBSTITUTED 6 ,14 -ETHENOMORPHINANS AND 7 -SUBSTITUTED 6 ,14 -ETHANOMORPHINANS | RHODES TECH (US) | 2019-08-07 | — | — | EP | disclosed |
| EP-3087079-B1 | OPIOID RECEPTOR MODULATING OXABICYCLO[2.2.2]OCTANE MORPHINANS | PURDUE PHARMA LP (US) | 2019-04-03 | — | — | EP | disclosed |
| US-10202382-B2 | Azamorphinan derivatives and use thereof | PURDUE PHARMA L.P. (US) | 2019-02-12 | — | — | US | disclosed |
| US-20180265510-A1 | 6,7-CYCLICMORPHINAN DERIVATIVES AND USE THEREOF | PURDUE PHARMA L.P. | 2018-09-20 | — | — | US | disclosed |
| WO-2014033530-A1 | 1,3-DIOXANOMORPHIDES AND 1,3-DIOXANOCODIDES | RHODES TECHNOLOGIES (US) | 2014-03-06 | — | — | WO | disclosed |
| US-20140057932-A1 | 1,3-Dioxanomorphides and 1,3-Dioxanocodides | RHODES TECHNOLOGIES (US) | 2014-02-27 | — | — | US | disclosed |
| EP-0823423-B1 | 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-06-16 | — | — | EP | disclosed |
| US-6140338-A | FOR TREATING ACUTE INFLAMMATORY DISEASES, CHRONIC INFLAMMATORY DISEASES, ACQUIRED IMMUNE DEFICIENCY SYNDROME, CANCER, ISCHEMIC REFLOW DISORDER AND/OR ARTERIOSCLEROSIS | BANYU PHARMACEUTICAL, CO., LTD. (JP) | 2000-10-31 | — | — | US | disclosed |
| US-6040449-A | USEFUL FOR FORMING FLUORINE CONTAINING 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES, USEFUL AS ANTAGONIST FOR MUSCARINIC M3 RECEPTORS AND LESS SIDE EFFECT | BANYU PHARMACEUTICAL CO LTD (JP) | 2000-03-21 | — | — | US | disclosed |
| US-5948792-A | POTENT AND SELECTIVE ANTAGONISTS FOR MUSCARINIC M.SUB.3 RECEPTORS WITH LITTLE SIDE EFFECTS. | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-09-07 | — | — | US | disclosed |
| EP-0930298-A1 | FLUORINATED 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-07-21 | — | — | EP | disclosed |
| EP-0916668-A1 | CHEMOKINE RECEPTOR ANTAGONISTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-05-19 | — | — | EP | disclosed |
| US-5750540-A | SIDE EFFECT REDUCTION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0823423-A1 | 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-02-11 | — | — | EP | disclosed |