SCHEMBL4461735

SCHEMBL4461735

CCC[CH]C1=CCCCC1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7992380 0.98 ALDH1A1 (0.32) ALDH1A1RAB9A
SCHEMBL7991290 0.98 ALDH1A1 (0.32) ALDH1A1RAB9A
SCHEMBL316395 0.94
SCHEMBL791251 0.88 PSMB5 (0.31) ALDH1A1RAB9A
SCHEMBL9211200 0.86 FAAH (0.33) ALDH1A1RAB9A
SCHEMBL61668 0.85 TSHR (0.33)
SCHEMBL68779 0.85
SCHEMBL7980376 0.83 CXCR3 (0.33) ALDH1A1RAB9A
SCHEMBL177598 0.83 CXCR3 (0.33) ALDH1A1RAB9A
SCHEMBL9213136 0.82 TSHR (0.30) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0227241-B1 Medicinal indole and indazole keto sulphone derivatives ZENECA INC (US) 1996-09-11 EP claimed
US-5234942-A Treating allergic pulmonary disorders, asthma ICI AMERICAS INC. (US) 1993-08-10 US claimed
EP-0242167-B1 HETEROCYCLIC CARBOXAMIDES ICI AMERICAS INC. (US) 1991-11-27 EP claimed
US-4997844-A Compounds for the treatment of allergic or inflammatory diseases or shock conditions ICI AMERICAS INC. (US) 1991-03-05 US claimed
EP-0179619-B1 HETEROCYCLIC AMIDES ICI AMERICAS INC. (US) 1990-09-05 EP claimed
US-4898863-A Heterocyclic carboxamides ICI AMERICAS INC. (US) 1990-02-06 US claimed
US-4837235-A ANTIALLERGENS, ANTIINFLAMMATORY AGENTS ICI AMERICAS INC. (US) 1989-06-06 US claimed
CN-87103504-A Heterocyclic carboxamide 1987-12-09 CN claimed
EP-0242167-A2 Heterocyclic carboxamides ICI AMERICAS INC. (US) 1987-10-21 EP claimed
EP-0227241-A2 Medicinal indole and indazole keto sulphone derivatives ZENECA INC. (US) 1987-07-01 EP claimed
CN-85108623-A Preparation has the novel method of the heterocycleamide of medical active 1986-07-30 CN claimed
EP-0179619-A1 Heterocyclic amides ICI AMERICAS INC. (US) 1986-04-30 EP claimed
WO-2024106539-A1 LIGAND CONJUGATE SUBSTANCE, NUCLEIC ACID CONTAINING SAME, AND USE THEREOF 株式会社ボナック 2024-05-23 WO disclosed
US-20230357767-A1 NOVEL NUCLEIC ACID MOLECULE INHIBITING EXPRESSION OF TARGET GENE BONAC CORPORATION (JP) 2023-11-09 US disclosed
EP-4206325-A1 NOVEL NUCLEIC ACID MOLECULE INHIBITING EXPRESSION OF TARGET GENE BONAC CORPORATION (JP) 2023-07-05 EP disclosed
US-20230183283-A1 NOVEL GLYCOSIDE COMPOUND AND PRODUCTION METHOD THEREFOR BONAC CORPORATION (JP) 2023-06-15 US disclosed
EP-0220066-A2 Carboxamide derivatives ICI AMERICAS INC. (US) 1987-04-29 EP disclosed
CN-86103278-A The method for preparing heterocyclic amide derivative 1986-12-17 CN disclosed
EP-0199543-A2 Heterocyclic amide derivatives ICI AMERICAS INC. (US) 1986-10-29 EP disclosed
EP-0179619-A1 Heterocyclic amides ICI AMERICAS INC. (US) 1986-04-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357767-A1 NOVEL NUCLEIC ACID MOLECULE INHIBITING EXPRESSION OF TARGET GENE SNRPE, DDX21, DCLRE1B ALDH1A1 3438/4885RAB9A 3603/4885
US-20230183283-A1 NOVEL GLYCOSIDE COMPOUND AND PRODUCTION METHOD THEREFOR SLC5A11, POLRMT, MAPK11 ALDH1A1 3258/4885RAB9A 2975/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.