Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7271114 | 0.82 | FAAH (0.47) | FAAHSPHK2SPHK1 | |
| SCHEMBL27511890 | 0.81 | CNR2 (0.35) | GBA1SIGMAR1FAAH | |
| SCHEMBL6402255 | 0.80 | MAPT (0.38) | MAPTSIGMAR1 | |
| SCHEMBL1875799 | 0.79 | LTA4H (0.38) | SIGMAR1FAAHALDH1A1 | |
| SCHEMBL1005038 | 0.79 | LTA4H (0.38) | SIGMAR1FAAHALDH1A1 | |
| SCHEMBL1005039 | 0.79 | LTA4H (0.38) | SIGMAR1FAAHALDH1A1 | |
| SCHEMBL3955729 | 0.79 | SIGMAR1 (0.53) | SIGMAR1ALDH1A1 | |
| SCHEMBL29302010 | 0.77 | CHRM2 (0.40) | MAPTSIGMAR1 | |
| SCHEMBL6585773 | 0.77 | MAPK1 (0.55) | MAPTRAB9ASIGMAR1FAAHALDH1A1 | |
| SCHEMBL1872881 | 0.76 | GBA1 (0.56) | GBA1MAPTNPC1RAB9ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0990653-B1 | 2-OXOIMIDAZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2004-09-15 | — | — | EP | disclosed |
| US-6258825-B1 | ANALGESIC, A RELIEVER AGAINST TOLERANCE TO A NARCOTIC ANALGESIC REPRESENTED BY MORPHINE, REMEDY FOR PARKINSONISM, A REMEDY FOR CHOREA, AN ANTIDEPRESSANT, A REMEDY FOR DIABETES INSIPIDUS, A REMEDY FOR POLYURIA, OR HYPOTENSION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| CN-1258294-A | 2-oxoimidazole derivs. | BANYU PHARMA CO LTD (JP) | 2000-06-28 | — | — | CN | disclosed |
| EP-0990653-A1 | 2-OXOIMIDAZOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-04-05 | — | — | EP | disclosed |