Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3955729 | 0.87 | SIGMAR1 (0.53) | SIGMAR1 | |
| SCHEMBL15872554 | 0.83 | SIGMAR1 (0.37) | MAPTSIGMAR1 | |
| SCHEMBL303965 | 0.83 | ALDH1A1 (0.35) | SIGMAR1 | |
| SCHEMBL29302010 | 0.83 | CHRM2 (0.40) | MAPTSIGMAR1TOP2A | |
| SCHEMBL7271114 | 0.83 | FAAH (0.47) | — | |
| SCHEMBL1005038 | 0.82 | LTA4H (0.38) | SIGMAR1 | |
| SCHEMBL1875799 | 0.82 | LTA4H (0.38) | SIGMAR1 | |
| SCHEMBL1005039 | 0.82 | LTA4H (0.38) | SIGMAR1 | |
| SCHEMBL21828897 | 0.80 | TOP2A (0.34) | MAPTSIGMAR1TOP2A | |
| SCHEMBL6589751 | 0.80 | GBA1 (0.41) | MAPTSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6852865-B2 | Catalytic carbonylation of three and four membered heterocycles | CORNELL RESEARCH FOUNDATION, INC. (US) | 2005-02-08 | — | — | US | disclosed |
| US-20030162961-A1 | Catalytic carbonylation of three and four membered heterocycles | CORNELL RESEARCH FOUNDATION, INC. | 2003-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162961-A1 | Catalytic carbonylation of three and four membered heterocycles | LOX, CA9, LPO | MAPT 4734/4885SIGMAR1 2604/4885TOP2A 441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.