Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6584722 | 0.79 | NPC1 (0.42) | TSHRCHRNA3NPC1 | |
| SCHEMBL13100535 | 0.72 | THRB (0.54) | NPC1THRBMAPT | |
| SCHEMBL13100536 | 0.68 | LMNA (0.49) | CHRNA3CHRNB4CHRNB2CHRNA4MAPT | |
| SCHEMBL24154367 | 0.67 | CHRNA3 (0.78) | CHRNA3CHRNB4CHRNB2CHRNA4 | |
| SCHEMBL1648049 | 0.65 | TSHR (0.63) | TSHRCHRNA3CHRNB4CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL30983201 | 0.65 | CHRNA3 (0.56) | CHRNA3CHRNB4CHRNB2CHRNA4 | |
| SCHEMBL905201 | 0.64 | CHRNA3 (0.81) | CHRNA3CHRNB4CHRNB2CHRNA4 | |
| SCHEMBL905236 | 0.64 | CHRNA3 (0.81) | CHRNA3CHRNB4CHRNB2CHRNA4 | |
| SCHEMBL3942452 | 0.64 | CHRNA3 (0.81) | CHRNA3CHRNB4CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL7840031 | 0.63 | CHRNA3 (0.78) | CHRNA3CHRNB4CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934308-B1 | 3-PYRIDYLOXYMETHYL HETEROCYCLIC ETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | ABBOTT LAB (US) | 2004-08-11 | — | — | EP | claimed |