Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | ECE1 | P42892 | 7/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ACACA | Q13085 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6080899 | 0.89 | PTGER4 (0.44) | KDM4EMMP2ECE1PDE10AACACA | |
| SCHEMBL6593501 | 0.88 | KDM4E (0.48) | KDM4EL3MBTL1MMP2ECE1GPR35 | |
| SCHEMBL1811192 | 0.82 | PDE10A (0.61) | KDM4EMMP2PDE10AALOX15ACACA | |
| SCHEMBL28231524 | 0.80 | ALOX15 (0.50) | KDM4EL3MBTL1MMP2ECE1PDE10A | |
| SCHEMBL8034930 | 0.80 | ADORA1 (0.51) | PDE10AACACANPC1PDE4BTNKS | |
| SCHEMBL6080627 | 0.80 | MMP2 (0.53) | KDM4EMMP2ALOX15TNKSTNKS2 | |
| SCHEMBL4704138 | 0.78 | KDM4E (0.55) | KDM4EL3MBTL1ECE1PDE10AALOX15 | |
| SCHEMBL6080905 | 0.77 | PDE10A (0.49) | KDM4EPDE10AALOX15ACACAPDE4B | |
| SCHEMBL6079925 | 0.76 | SLC6A4 (0.44) | KDM4EL3MBTL1NPC1PDE4BALDH1A1 | |
| SCHEMBL6079947 | 0.75 | ACACA (0.55) | KDM4EMMP2PDE10AALOX15ACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | claimed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | claimed |
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | disclosed |