Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.41 |
| ▸ | EIF4E | P06730 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6594275 | 1.00 | MEN1 (0.50) | MEN1KMT2AMMP2ALDH1A1TDP1 | |
| SCHEMBL6080149 | 0.87 | APP (0.48) | MEN1KMT2AMMP2ALDH1A1TDP1 | |
| SCHEMBL6590529 | 0.82 | KMT2A (0.48) | MEN1KMT2AALDH1A1TDP1GPR35 | |
| SCHEMBL6080952 | 0.82 | KMT2A (0.48) | MEN1KMT2AALDH1A1TDP1GPR35 | |
| SCHEMBL10371789 | 0.81 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1TDP1MAPT | |
| SCHEMBL6591021 | 0.81 | MEN1 (0.54) | MEN1KMT2AALDH1A1TDP1GPR35 | |
| SCHEMBL6591013 | 0.81 | MEN1 (0.54) | MEN1KMT2AALDH1A1TDP1GPR35 | |
| SCHEMBL6052793 | 0.80 | MMP2 (0.53) | MMP2ALDH1A1TDP1MAPTGRM2 | |
| SCHEMBL6079734 | 0.79 | MMP2 (0.54) | MEN1KMT2AMMP2ALDH1A1MAPT | |
| SCHEMBL6080455 | 0.78 | HCAR3 (0.47) | MEN1KMT2AMMP2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | claimed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | claimed |
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | disclosed |