SCHEMBL6592103

SCHEMBL6592103

CC(=O)Nc1c[c]c(S(=O)(=O)O)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 5/20 0.46
CA2 P00918 5/20 0.46
CA9 Q16790 4/20 0.46
CA12 O43570 3/20 0.46
SMN1; SMN2 Q16637 4/20 0.46
HTT P42858 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
HPGD P15428 2/20 0.45
MMP1 P03956 1/20 0.45
MMP2 P08253 1/20 0.45
MMP9 P14780 1/20 0.45
MMP8 P22894 1/20 0.45
MMP13 P45452 1/20 0.45
ALDH1A1 P00352 4/20 0.44
KMT2A Q03164 3/20 0.44
MEN1 O00255 2/20 0.44
MAPT P10636 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
BRD4 O60885 1/20 0.44
NR1I2 O75469 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3374952 0.78 RXFP1 (0.30)
SCHEMBL3914583 0.75 ENPP2 (0.49) CA1CA2CA9CA12SMN1; SMN2
SCHEMBL973371 0.74 KMT2A (0.55) CA1CA2CA9CA12SMN1; SMN2
SCHEMBL9770987 0.74 LMNA (0.50) CA1CA2CA9CA12SMN1; SMN2
SCHEMBL3377417 0.74 ALDH1A1 (0.37) CA1CA2CA9CA12ALDH1A1
SCHEMBL1740872 0.74 TDP1 (0.55) CA1CA2CA9CA12SMN1; SMN2
SCHEMBL2683899 0.73 SMN1; SMN2 (0.50) CA1CA2CA9CA12SMN1; SMN2
SCHEMBL27544478 0.73 SMN1; SMN2 (0.50) CA1CA2CA9CA12SMN1; SMN2
SCHEMBL95120 0.73 SMN1; SMN2 (0.50) CA1CA2CA9CA12SMN1; SMN2
SCHEMBL3064656 0.73 SMN1; SMN2 (0.50) CA1CA2CA9CA12SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1029002-B1 REACTIVE DYES CONTAINING A HALOBENZENE NUCLEUS DYSTAR TEXTILFARBEN GMBH & CO (DE) 2004-05-12 EP disclosed
US-20030191293-A1 Reactive dyes containing a halobenzene nucleus BASF AKIENGESELLSCHAFT (DE) 2003-10-09 US disclosed
US-20030158395-A1 Reactive dyes containing a halobenzene nucleus BASF AKIENGESELLSCHAFT (DE) 2003-08-21 US disclosed
EP-1333062-A1 Reactive dyes containing a halobenzene nucleus DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2003-08-06 EP disclosed
EP-0765965-B1 Process for deying synthetic fibrous polyamid materials DYSTAR TEXTILFARBEN GMBH & CO (DE) 2003-06-04 EP disclosed
WO-2003006560-A2 AQUEOUS INK FORMULATIONS FOR INKJET PRINTING DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2003-01-23 WO disclosed
US-6399751-B1 REACTION PRODUCT BASF AKTIENGESELLSCHAFT (DE) 2002-06-04 US disclosed
EP-1127923-A2 Water-soluble fibre-reactive dyestuffs, process for their preparation and their use DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2001-08-29 EP disclosed
EP-0876430-B1 BRANCHED POLYAMINE LINKED REACTIVE DYES AND COLORATION PROCESS USING THEM SYNGENTA LTD (GB) 2001-08-29 EP disclosed
EP-0971986-B1 REACTIVE DYES CONTAINING A PERMANENT QUATERNARY AMMONIUM GROUP DYSTAR L P (US) 2001-06-27 EP disclosed
EP-0471702-A1 WATER-SOLUBLE REACTIVE DYES FOR FIBRES, THEIR PREPARATION AND USE. HOECHST AG (DE) 1992-02-26 EP disclosed
WO-1991010709-A1 WATER-SOLUBLE DYES WHICH REACT WITH FIBRES, PROCESS FOR PRODUCING THEM AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1991-07-25 WO disclosed
US-5021558-A Color strength, fastness HOECHST AKTIENGESELLSCHAFT (DE) 1991-06-04 US disclosed
WO-1990013604-A1 WATER-SOLUBLE REACTIVE DYES FOR FIBRES, THEIR PREPARATION AND USE HOECHST AKTIENGESELLSCHAFT (DE) 1990-11-15 WO disclosed
EP-0388864-A2 Water-soluble, fibre-reactive dyes, method of their preparation and use HOECHST AKTIENGESELLSCHAFT (DE) 1990-09-26 EP disclosed
EP-0385426-A1 Water soluble reactive dyes, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1990-09-05 EP disclosed
EP-0385204-A1 Water-soluble, fibre-reactive azo dyestuffs, their bis(carbonamido)-benzo precursors, methods for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1990-09-05 EP disclosed
EP-0374911-A1 Water-soluble, fibre-reactive dyes, methods for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1990-06-27 EP disclosed
EP-0361440-A1 Water soluble fibre-reactive dyes, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1990-04-04 EP disclosed
EP-0354409-A1 Fibre-reactive dyes, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1990-02-14 EP disclosed