Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.43 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.41 |
| ▸ | ECE1 | P42892 | 2/20 | 0.40 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 2/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6591608 | 0.90 | MCL1 (0.51) | ALOX15GPR35PDE10AALDH1A1KDM4E | |
| SCHEMBL6081303 | 0.90 | DHODH (0.43) | ALOX15PDE10AALDH1A1KDM4EDHODH | |
| SCHEMBL6080080 | 0.83 | MCL1 (0.46) | ALDH1A1KDM4EMCL1DHODH | |
| SCHEMBL6592298 | 0.81 | MCL1 (0.53) | MCL1DHODH | |
| SCHEMBL6593629 | 0.81 | ALOX5 (0.49) | ALOX15GPR35PDE10AKDM4EIGFBP3 | |
| SCHEMBL6594680 | 0.81 | ALOX15 (0.48) | ALOX15GPR35PDE10AALDH1A1KDM4E | |
| SCHEMBL6079795 | 0.81 | ALOX15 (0.48) | ALOX15GPR35PDE10AALDH1A1KDM4E | |
| SCHEMBL975858 | 0.81 | ALOX15 (0.56) | ALOX15GPR35PDE10AALDH1A1KDM4E | |
| SCHEMBL6599593 | 0.81 | GPR35 (0.52) | ALOX15GPR35PDE10AALDH1A1KDM4E | |
| SCHEMBL6593859 | 0.81 | GPR35 (0.56) | ALOX15GPR35ALDH1A1KDM4EIGFBP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | claimed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | claimed |
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | disclosed |