Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.53 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.53 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.53 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.53 |
| ▸ | CBFB | Q13951 | 1/20 | 0.53 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6080447 | 0.86 | SMN1; SMN2 (0.54) | KDM4EKMT2AMAPTNPC1RAB9A | |
| SCHEMBL2907650 | 0.81 | IGFBP3 (0.43) | KDM4EMAPTRAB9AALDH1A1PKM | |
| SCHEMBL2905327 | 0.77 | GRM2 (0.49) | KDM4EKMT2AMAPTRAB9AMEN1 | |
| SCHEMBL2905794 | 0.77 | IGFBP5 (0.46) | KDM4EMAPTRAB9AALDH1A1 | |
| SCHEMBL2902980 | 0.75 | ALOX15 (0.47) | KDM4EKMT2AMAPTNPC1RAB9A | |
| SCHEMBL6080450 | 0.75 | KDM4E (0.51) | KDM4EKMT2AMAPTNPC1RAB9A | |
| SCHEMBL2909734 | 0.74 | MCL1 (0.44) | KDM4EKMT2ANPC1MEN1ALDH1A1 | |
| SCHEMBL2909106 | 0.74 | IGFBP5 (0.45) | KDM4EALDH1A1 | |
| SCHEMBL9398468 | 0.74 | IGFBP5 (0.43) | KDM4EMAPTRAB9A | |
| 7-Chlorokynurenic Acid SCHEMBL29386783 | 0.74 | IGFBP3 (0.47) | KMT2AALDH1A1POLBCYP1A2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | claimed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | claimed |
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | disclosed |