Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGFBP5 | P24593 | 6/20 | 0.43 |
| ▸ | IGFBP3 | P17936 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | IGFBP1 | P08833 | 1/20 | 0.36 |
| ▸ | IGFBP2 | P18065 | 1/20 | 0.36 |
| ▸ | IGFBP4 | P22692 | 1/20 | 0.36 |
| ▸ | IGFBP6 | P24592 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4471851 | 0.88 | IGFBP5 (0.41) | IGFBP5IGFBP3ALOX15TSHRHIF1A | |
| SCHEMBL9398497 | 0.85 | NQO2 (0.47) | APP | |
| SCHEMBL2905794 | 0.83 | IGFBP5 (0.46) | IGFBP5IGFBP3ALOX15TSHRHIF1A | |
| SCHEMBL2902980 | 0.81 | ALOX15 (0.47) | IGFBP5IGFBP3ALOX15TSHRHIF1A | |
| 7-Chlorokynurenic Acid SCHEMBL29386783 | 0.80 | IGFBP3 (0.47) | IGFBP5IGFBP3HIF1A | |
| SCHEMBL2909734 | 0.80 | MCL1 (0.44) | IGFBP5IGFBP3ALOX15KDM4E | |
| 7-Chlorokynurenic Acid SCHEMBL157187 | 0.80 | IGFBP3 (0.47) | IGFBP5IGFBP3HIF1A | |
| 7-Chlorokynurenic Acid SCHEMBL31238955 | 0.80 | IGFBP3 (0.47) | IGFBP5IGFBP3HIF1A | |
| SCHEMBL2909106 | 0.80 | IGFBP5 (0.45) | IGFBP5IGFBP3ALOX15KDM4E | |
| SCHEMBL2905327 | 0.80 | GRM2 (0.49) | IGFBP5IGFBP3ALOX15KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5344922-A | 4-hydroxyquinaldic acid derivatives | BOARD OF REGENTS, UNIVERSITY OF TEXAS | 1994-09-06 | — | — | US | disclosed |
| US-5028707-A | 4-hydroxyquinaldic acid derivatives | BOARD OF REGENTS, UNIVERSITY OF TEXAS (US) | 1991-07-02 | — | — | US | disclosed |
| WO-1991007390-A1 | 4-HYDROXYQUINALDIC ACID DERIVATIVES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1991-05-30 | — | — | WO | disclosed |