Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 5/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | ILK | Q13418 | 10/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7772384 | 0.81 | HDAC3 (0.44) | STING1MEN1NPC1ALDH1A1RAB9A | |
| SCHEMBL17842709 | 0.71 | STING1 (0.66) | STING1CHRNA7 | |
| SCHEMBL19756737 | 0.71 | STING1 (0.46) | STING1CHRNA7ILKRAB9A | |
| SCHEMBL16063135 | 0.70 | STING1 (0.42) | STING1CHRNA7ILKMEN1NPC1 | |
| SCHEMBL6598617 | 0.70 | SRD5A1 (0.46) | STING1CHRNA7MEN1NPC1RAB9A | |
| SCHEMBL6142155 | 0.69 | CA2 (0.51) | MEN1NPC1ALDH1A1RAB9AKMT2A | |
| SCHEMBL4804570 | 0.69 | GRM1 (0.35) | KCNH2MEN1NPC1ALDH1A1RAB9A | |
| SCHEMBL19756674 | 0.67 | RAB9A (0.40) | STING1ILKMEN1NPC1ALDH1A1 | |
| SCHEMBL10286982 | 0.67 | STING1 (0.42) | STING1ILK | |
| SCHEMBL2937347 | 0.66 | LMNA (0.46) | HTR1ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863755-B1 | ANTITHROMBOTIC DIAMINES | LILLY CO ELI (US) | 2004-12-15 | — | — | EP | disclosed |
| US-6265575-B1 | THROMBIN INHIBITORS | ELI LILLY AND COMPANY | 2001-07-24 | — | — | US | disclosed |
| US-6251921-B1 | ADMINISTERING THROMBIN INHIBITING DIAMINE COMPOUND TO MAMMAL | ELI LILLY AND COMPANY | 2001-06-26 | — | — | US | disclosed |
| US-6025382-A | Antithrombotic diamines | ELI LILLY AND COMPANY (US) | 2000-02-15 | — | — | US | disclosed |
| EP-0863755-A4 | ANTITHROMBOTIC DIAMINES | LILLY CO ELI (US) | 1999-01-20 | — | — | EP | disclosed |
| EP-0863755-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997025033-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |