Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.33 |
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | CTSS | P25774 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6587818 | 0.82 | CTSK (0.36) | CTSKCTSLCTSS | |
| SCHEMBL5096433 | 0.81 | CTSK (0.42) | CTSKCTSLCTSS | |
| SCHEMBL5092894 | 0.77 | CTSK (0.35) | CTSKCTSLCTSS | |
| SCHEMBL5092532 | 0.76 | CTSK (0.38) | CTSKCTSLCTSS | |
| SCHEMBL5105613 | 0.75 | ALDH1A1 (0.38) | — | |
| SCHEMBL5099273 | 0.74 | CTSK (0.40) | CTSKCTSLCTSS | |
| SCHEMBL5099688 | 0.73 | ACHE (0.34) | CTSK | |
| SCHEMBL5092868 | 0.73 | CTSK (0.35) | CTSKCTSLCTSS | |
| SCHEMBL4902762 | 0.73 | RAB9A (0.41) | CTSKCTSLCTSS | |
| SCHEMBL5098964 | 0.72 | BIRC2 (0.37) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307204-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2004-06-02 | — | — | EP | disclosed |
| EP-1307204-A1 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2003-05-07 | — | — | EP | disclosed |
| WO-2001095911-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-12-20 | — | — | WO | disclosed |