SCHEMBL6594973

SCHEMBL6594973

CCOP(=O)(OCC)C(C)Oc1c[c]c(F)cc1Cl

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.35
POLB P06746 2/20 0.35
LMNA P02545 4/20 0.34
KDM4E B2RXH2 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
TDP1 Q9NUW8 1/20 0.31
GAA P10253 2/20 0.30
THRB P10828 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6588915 0.81 LMNA (0.31) LMNAKDM4EL3MBTL1GAAMEN1
SCHEMBL7931498 0.76 SLC2A1 (0.33)
SCHEMBL6594344 0.76 TDP1 (0.32) TDP1MEN1KMT2A
SCHEMBL1531081 0.75 CSNK2A1 (0.41) POLBLMNAKDM4ETDP1GAA
SCHEMBL6592765 0.75 PPOX (0.48) MAPTLMNAKDM4EL3MBTL1TDP1
SCHEMBL7741275 0.72 KDM4E (0.33) LMNAKDM4EGAAMEN1KMT2A
SCHEMBL5843254 0.72 MAPT (0.37) MAPTLMNAKDM4EL3MBTL1KMT2A
SCHEMBL1531114 0.69
SCHEMBL6596714 0.69 ALDH1A1 (0.39) MAPTLMNAKDM4EL3MBTL1TDP1
SCHEMBL5843340 0.68 TSHR (0.38) MAPTLMNAL3MBTL1TDP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1171879-C Herbicidal 3-aryl-1,2,4-triazole derivative 拜尔公司 2004-10-20 CN disclosed
EP-1120411-B1 4-Aryl-1,2,4-triazolidinedione derivatives and their use as herbicides BAYER CROPSCIENCE AG (DE) 2004-09-22 EP disclosed
US-20030208073-A1 Substituted N-aryl nitrogen-containing heterocyclic compounds LINKER KARL-HEINZ (DE) 2003-11-06 US disclosed
EP-1120411-A2 4-Aryl-1,2,4-triazolidinedione derivatives and their use as herbicides BAYER AG (DE) 2001-08-01 EP disclosed
US-6162765-A Substituted N-aryl nitrogen-containing heterocyclic compounds BAYER AKTIENGESELLSCHAFT (DE) 2000-12-19 US disclosed
WO-2000016742-A1 CHEWABLE COMPOSITIONS CONTAINING DEXTROMETHORPHAN THE PROCTER & GAMBLE COMPANY (US) 2000-03-30 WO disclosed
EP-0797573-A1 3-ARYL-1,2,4-TRIAZOLE DERIVATIVES WITH HERBICIDAL PROPERTIES BAYER AG (DE) 1997-10-01 EP disclosed
WO-1997026248-A1 SUBSTITUTED N-ARYL NITROGEN HETEROCYCLIC COMPOUNDS AND THEIR USE AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-07-24 WO disclosed
WO-1996018618-A1 3-ARYL-1,2,4-TRIAZOLE DERIVATIVES WITH HERBICIDAL PROPERTIES BAYER AKTIENGESELLSCHAFT (DE) 1996-06-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030208073-A1 Substituted N-aryl nitrogen-containing heterocyclic compounds NAT1, CYP1B1, CYP1A1 MAPT 3893/4885POLB 2777/4885LMNA 1834/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.