Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5359685 | 0.99 | SMYD3 (0.35) | SMYD3CRHR1MAPTGFERSMN1; SMN2 | |
| SCHEMBL6596459 | 0.83 | KMT2A (0.45) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL1193919 | 0.82 | KMT2A (0.44) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL6596219 | 0.80 | MAPT (0.35) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL6598839 | 0.79 | HTT (0.35) | SMN1; SMN2THRBMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL1193715 | 0.79 | MAPT (0.34) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL6597984 | 0.79 | MAPK8 (0.39) | ROCK2ROCK1MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL5361934 | 0.79 | HTT (0.35) | SMN1; SMN2THRBMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL1194003 | 0.78 | MAPK8 (0.39) | ROCK2ROCK1MEN1KMT2AALDH1A1 | |
| SCHEMBL6598655 | 0.77 | MEN1 (0.38) | SMN1; SMN2MEN1KMT2AALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373263-B1 | HETEROCYCLIC COMPOUNDS FOR AGING-RELATED AND DIABETIC VASCULAR COMPLICATIONS | TORRENT PHARMACEUTICALS LTD (IN) | 2004-10-27 | — | — | EP | claimed |