SCHEMBL659527

SCHEMBL659527

Cc1cc(C)c2c(c1C)OC(C)(C)C2

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
LMNA P02545 1/20 0.39
HTT P42858 1/20 0.39
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
EZH2 Q15910 1/20 0.33
KDM4E B2RXH2 1/20 0.32
HPGD P15428 1/20 0.32
DHFR P00374 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29494119 1.00 ALDH1A1 (0.39) ALDH1A1SMN1; SMN2LMNAHTTCYP1A2
SCHEMBL8877823 0.84 ALDH1A1 (0.36) ALDH1A1SMN1; SMN2LMNAHTTCYP1A2
SCHEMBL8117537 0.81 ALDH1A1 (0.38) ALDH1A1SMN1; SMN2LMNAHTTCYP1A2
SCHEMBL658520 0.81 ALDH1A1 (0.38) ALDH1A1SMN1; SMN2LMNAHTTCYP1A2
SCHEMBL837194 0.81 HPGD (0.37) ALDH1A1SMN1; SMN2LMNACYP1A2CYP3A4
Hydrochloric Acid SCHEMBL8117330 0.79 ALDH1A1 (0.37) ALDH1A1SMN1; SMN2LMNAHTTCYP1A2
SCHEMBL2819365 0.78
SCHEMBL658720 0.78 ALDH1A1 (0.36) ALDH1A1SMN1; SMN2LMNAHTTCYP1A2
SCHEMBL6987008 0.78
SCHEMBL29793360 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2024-12-05 US claimed
CN-104586752-B A kind of glucose-sensitive self-discipline formula insulin releasing microgel carrier and preparation method thereof 湖北大学 2017-09-01 CN claimed
EP-4230219-B1 PHARMACEUTICAL COMPOSITION COMPRISING GLUCAGON/GLP-1/GIP TRIPLE AGONIST OR LONG-ACTING CONJUGATE THEREOF FOR PREVENTING OR TREATING LUPUS-RELATED DISEASES HANMI PHARMACEUTICAL CO LTD (KR) 2026-04-08 EP disclosed
US-12552850-B2 GLP-1/GIP dual agonist, long-acting conjugate thereof, and pharmaceutical composition comprising same HANMI PHARM. CO., LTD. (KR) 2026-02-17 US disclosed
US-20260022143-A1 Cyclic Peptide Inhibitors of IL-23 JANSSEN PHARMACEUTICA NV (BE) 2026-01-22 US disclosed
US-20260007787-A1 RADIOPHARMACEUTICAL SMALL MOLECULE INHIBITORS OF FIBROBLAST ACTIVATION PROTEIN FOR TARGETED THERAPY AND DIAGNOSTIC IMAGING OF DESMOPLASTIC TUMORS TRUSTEES OF TUFTS COLLEGE 2026-01-08 US disclosed
EP-3592761-B1 NEW ANTIBACTERIAL PRODUCTS UNIV LIVERPOOL (GB) 2025-05-14 EP disclosed
WO-2025082461-A1 POLYPEPTIDE, BIOACTIVE CONJUGATE, AND PREPARATION METHOD THEREFOR AND USE THEREOF 优洛生物(上海)有限公司 2025-04-24 WO disclosed
US-20250026763-A1 EGFR INHIBITORS AND METHODS OF USE THEREOF Allorion Therapeutics Inc 2025-01-23 US disclosed
WO-2024256834-A1 TEIXOBACTINS ANALOGUES AS ANTI-BIOFILM AGENTS UNIVERSITY OF LIVERPOOL (GB) 2024-12-19 WO disclosed
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2024-12-05 US disclosed
EP-1614684-A1 DIAMINE DERIVATIVE, PRODUCTION PROCESS, AND ANTIOXIDIZING DRUG NIPPON SODA CO., LTD. (JP) 2006-01-11 EP disclosed
US-6867011-B1 Synthetic bioepitope compounds which can be used as standards in the biological assays of Troponin I BIO-RAD PASTEUR (FR) 2005-03-15 US disclosed
US-6822074-B1 COMPRISES CYCLIZATION OF PRECURSOR; FOR IMPROVED YIELD MERCK PATENT GMBH (DE) 2004-11-23 US disclosed
WO-1999051625-A9 PEPTIDES CAUSING FORMATION OF COMPACT STRUCTURES RIGEL PHARMACEUTICALS INC (US) 2001-07-05 WO disclosed
EP-1071705-A2 PEPTIDES CAUSING FORMATION OF COMPACT STRUCTURES Rigel Pharmaceuticals, Inc. (US) 2001-01-31 EP disclosed
WO-1999051625-A2 PEPTIDES CAUSING FORMATION OF COMPACT STRUCTURES RIGEL PHARMACEUTICALS, INC. (US) 1999-10-14 WO disclosed
CN-1174704-A Medicinal composition for inhibiting fat peroxide forming TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1998-03-04 CN disclosed
US-5631208-A Herbicidal cyclohexane-1,3-dione derivatives and their preparation process KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1997-05-20 US disclosed
WO-1994003443-A1 HERBICIDAL CYCLOHEXANE-1,3-DIONE DERIVATIVES AND THEIR PREPARATION PROCESS KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1994-02-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260007787-A1 RADIOPHARMACEUTICAL SMALL MOLECULE INHIBITORS OF FIBROBLAST ACTIVATION PROTEIN FOR TARGETED THERAPY AND DIAGNOSTIC IMAGING OF DESMOPLASTIC TUMORS FIBP, FRS2, FGFR1 ALDH1A1 2378/4885SMN1; SMN2 4443/4885LMNA 1947/4885
US-20260022143-A1 Cyclic Peptide Inhibitors of IL-23 IL23R, IL17A, IL36G ALDH1A1 4865/4885SMN1; SMN2 2640/4885LMNA 1399/4885
US-12552850-B2 GLP-1/GIP dual agonist, long-acting conjugate thereof, and pharmaceutical composition comprising same GLP1R, VIP, GIPR ALDH1A1 4041/4885SMN1; SMN2 2546/4885LMNA 4432/4885
US-20250026763-A1 EGFR INHIBITORS AND METHODS OF USE THEREOF EGFR, ERBB3, ERBB2 ALDH1A1 4536/4885SMN1; SMN2 4856/4885LMNA 4866/4885
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES BCAT1, BCAT2, PELP1 ALDH1A1 4472/4885SMN1; SMN2 4155/4885LMNA 4108/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.