Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP12 | P39900 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6596772 | 0.92 | MMP2 (0.42) | MMP2MMP12MCL1XDHPTGER1 | |
| SCHEMBL6080047 | 0.91 | MMP2 (0.41) | MMP2MMP12MCL1XDHALDH1A1 | |
| SCHEMBL6079883 | 0.90 | MMP2 (0.41) | MMP2MMP12ALDH1A1SMN1; SMN2 | |
| SCHEMBL6614590 | 0.88 | CTSV (0.39) | MMP2MMP12MCL1 | |
| SCHEMBL6079888 | 0.83 | MMP2 (0.40) | MMP2MMP12XDHPTGER1ALDH1A1 | |
| SCHEMBL6080053 | 0.82 | MMP2 (0.39) | MMP2MMP12MCL1PTGER1ALDH1A1 | |
| SCHEMBL6598552 | 0.82 | XDH (0.42) | MMP2MMP12MCL1XDHPTGER1 | |
| SCHEMBL6591840 | 0.81 | MRGPRX4 (0.43) | MMP2MMP12MCL1XDHPTGER1 | |
| SCHEMBL6080108 | 0.79 | APP (0.41) | MMP2MMP12ALDH1A1SMN1; SMN2 | |
| SCHEMBL6079838 | 0.78 | MMP2 (0.31) | MMP2MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | claimed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | claimed |
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | disclosed |