Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 4/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 6/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6080093 | 0.92 | MMP2 (0.36) | XDHPTGER1MMP2MMP12ALDH1A1 | |
| SCHEMBL6596273 | 0.86 | XDH (0.44) | XDHPTGER1MCL1P4HTM | |
| SCHEMBL6596521 | 0.85 | XDH (0.40) | XDHPTGER1MCL1SMN1; SMN2 | |
| SCHEMBL6595349 | 0.82 | MMP2 (0.43) | XDHPTGER1MCL1MMP2MMP12 | |
| SCHEMBL6591840 | 0.82 | MRGPRX4 (0.43) | XDHPTGER1MCL1MMP2MMP12 | |
| SCHEMBL6080097 | 0.80 | MMP2 (0.37) | XDHPTGER1MCL1MMP2MMP12 | |
| SCHEMBL6597779 | 0.79 | CTSV (0.41) | XDH | |
| SCHEMBL6080107 | 0.79 | ADORA3 (0.39) | XDHPTGER1MCL1 | |
| SCHEMBL6080213 | 0.78 | CTSL (0.44) | XDHALDH1A1SMN1; SMN2 | |
| SCHEMBL6596585 | 0.78 | THRA (0.45) | PTGER1MCL1P4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | claimed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | claimed |
| EP-1451159-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003010146-A1 | COMPOSITIONS DERIVED FROM QUINOLINE AND QUINOXALINE, PREPARATION AND USE THEREOF | NEURO3D (FR) | 2003-02-06 | — | — | WO | disclosed |