Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PRCP | P42785 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15850531 | 0.88 | SLC6A3 (0.46) | SLC6A3SLC6A2SLC6A4MEN1PRCP | |
| SCHEMBL30207567 | 0.81 | SLC6A2 (0.45) | SLC6A3SLC6A2SLC6A4MEN1PRCP | |
| SCHEMBL30207525 | 0.81 | SLC6A2 (0.45) | SLC6A3SLC6A2SLC6A4MEN1PRCP | |
| SCHEMBL6916553 | 0.77 | CHRM3 (0.48) | SLC6A3SLC6A2SLC6A4MEN1PRCP | |
| SCHEMBL7706916 | 0.76 | SLC6A3 (0.42) | SLC6A3SLC6A2SLC6A4MEN1PRCP | |
| SCHEMBL6597123 | 0.75 | SLC6A2 (0.41) | SLC6A3SLC6A2SLC6A4MEN1KMT2A | |
| SCHEMBL6595795 | 0.74 | SLC6A3 (0.40) | SLC6A3SLC6A2SLC6A4MEN1PRCP | |
| Gacyclidine SCHEMBL4465879 | 0.73 | SIGMAR1 (0.57) | SLC6A3SLC6A2SLC6A4MEN1PRCP | |
| Gacyclidine SCHEMBL7190367 | 0.73 | SIGMAR1 (0.57) | SLC6A3SLC6A2SLC6A4MEN1PRCP | |
| Gacyclidine SCHEMBL3457748 | 0.73 | SIGMAR1 (0.57) | SLC6A3SLC6A2SLC6A4MEN1PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915867-B1 | THIENYLCYCLOHEXANE DERIVATIVES FOR THIENYLCYCLOHEXYL SYNTHESIS | SOD CONSEILS RECH APPLIC (FR) | 2004-10-06 | — | — | EP | disclosed |
| US-6107495-A | REACTING SPECIFIED 1-(2- OR 3-THIENYL) CYCLOHEXANES WITH A 1,5-DIHALOPENTANE TO FORM CYCLIC (THIENYLCYCLOHEXYL)AMINES SUCH AS 2-ALKYL-(3-THIENYL)CYCLOHEXYL PIPERIDINE; USE AS INTERMEDIATES TO RADIOACTIVE LABELLED MOLECULES | SOCIETE D'EXPANSION SCIENTIFIQUE EXPANSIA (FR) | 2000-08-22 | — | — | US | disclosed |
| US-5972952-A | THERAPY FOR STROKE, NERVOUS SYSTEM DISORDERS, ALZHEIMER'SDISEASE | LE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1999-10-26 | — | — | US | disclosed |
| EP-0915867-A1 | THIENYLCYCLOHEXANE DERIVATIVES FOR THIENYLCYCLOHEXYL SYNTHESIS | Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.) (FR) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998003498-A1 | THIENYLCYCLOHEXANE DERIVATIVES FOR THIENYLCYCLOHEXYL SYNTHESIS | SOCIETE D'EXPANSION SCIENTIFIQUE EXPANSIA (FR) | 1998-01-29 | — | — | WO | disclosed |