Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 2/20 | 0.46 |
| ▸ | CLK2 | P49760 | 1/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 4/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6592058 | 0.75 | HIF1A (0.50) | CLK1CLK2HCRTR1HCRTR2PIN1 | |
| SCHEMBL6592930 | 0.72 | MTNR1A (0.53) | CLK1CLK2HCRTR1HCRTR2MCHR1 | |
| SCHEMBL6590841 | 0.71 | CLK1 (0.46) | CLK1CLK2HCRTR1HCRTR2PIN1 | |
| SCHEMBL6596424 | 0.71 | CLK1 (0.46) | CLK1CLK2HCRTR1HCRTR2PIN1 | |
| SCHEMBL5277894 | 0.70 | HPGD (0.58) | HCRTR1HCRTR2PIN1ALDH1A1 | |
| SCHEMBL4342983 | 0.67 | CTSD (0.65) | CLK1CLK2PIN1LMNASMN1; SMN2 | |
| SCHEMBL6589300 | 0.66 | CA1 (0.41) | CLK1CLK2HCRTR1HCRTR2PIN1 | |
| SCHEMBL19014242 | 0.65 | PLK1 (0.53) | CLK1CLK2PIN1ALDH1A1LMNA | |
| SCHEMBL17067305 | 0.64 | ATM (0.62) | — | |
| SCHEMBL24268476 | 0.64 | SMN1; SMN2 (0.50) | CLK1CLK2HCRTR1HCRTR2PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842927-B1 | 3-Amido-chromanylsulfonyl(thio)ureas, process for their preparation, their use and medicaments containing them | AVENTIS PHARMA GMBH (DE) | 2004-02-25 | — | — | EP | disclosed |
| US-5849755-A | 3-amidochromanylsulfonyl(thio)ureas, processes for their preparation, their use, and pharmaceutical preparations comprising them | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-12-15 | — | — | US | disclosed |
| EP-0842927-A1 | 3-Amido-chromanylsulfonyl(thio)ureas, process for their preparation, their use and medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-05-20 | — | — | EP | disclosed |