Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | AGXT | P21549 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30444190 | 0.80 | CYP2A6 (0.43) | CYP2A6ADRB2ASIC3LOXL2AGXT | |
| SCHEMBL19557296 | 0.80 | CYP2A6 (0.43) | CYP2A6ADRB2ASIC3LOXL2AGXT | |
| SCHEMBL17856939 | 0.78 | CYP2A6 (0.44) | CYP2A6ADRB2ASIC3LOXL2AGXT | |
| SCHEMBL30444116 | 0.78 | CYP2A6 (0.44) | CYP2A6ADRB2ASIC3LOXL2AGXT | |
| SCHEMBL15274417 | 0.77 | NPC1 (0.31) | — | |
| SCHEMBL28514083 | 0.75 | BCL2L1 (0.44) | CYP2A6ADRB2ASIC3LOXL2AGXT | |
| SCHEMBL31141892 | 0.75 | BCL2L1 (0.44) | CYP2A6ADRB2ASIC3LOXL2AGXT | |
| SCHEMBL6813386 | 0.75 | APP (0.41) | CYP2A6APP | |
| SCHEMBL18271669 | 0.75 | MGLL (0.42) | CYP2A6ADRB2ASIC3LOXL2AGXT | |
| SCHEMBL1249028 | 0.74 | HSP90AA1 (0.47) | CYP2A6APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10836723-B2 | Method for synthesizing sodium 2,2,6,6-tetramethylpiperidides | KOBELCO ECO-SOLUTIONS CO., LTD. (JP) | 2020-11-17 | — | — | US | disclosed |
| US-9073938-B2 | Method for producing aromatic compound | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2015-07-07 | — | — | US | disclosed |
| US-9073938-B2 | Method for producing aromatic compound | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2015-07-07 | — | — | US | disclosed |
| US-20100137617-A1 | METHOD FOR PRODUCING AROMATIC COMPOUND | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2010-06-03 | — | — | US | disclosed |
| EP-1204660-B1 | SEROTONERGIC BENZOTHIOPHENES | LILLY CO ELI (US) | 2004-10-20 | — | — | EP | disclosed |
| EP-1204660-A1 | SEROTONERGIC BENZOTHIOPHENES | ELI LILLY AND COMPANY (US) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001009126-A1 | SEROTONERGIC BENZOTHIOPHENES | ELI LILLY AND COMPANY (US) | 2001-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137617-A1 | METHOD FOR PRODUCING AROMATIC COMPOUND | SCLY, TYR, CBS | CYP2A6 342/4885ADRB2 733/4885ASIC3 2249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.