Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6597369 | 0.85 | GRM5 (0.57) | GRM5L3MBTL1RAB9AMAPTHPGD | |
| SCHEMBL7266190 | 0.82 | GRM5 (0.39) | GRM5TRPA1L3MBTL1RAB9AMAPT | |
| SCHEMBL5547177 | 0.76 | GRM5 (0.43) | GRM5MEN1KMT2AKDM4E | |
| SCHEMBL6603575 | 0.72 | CHRNB2 (0.44) | RAB9AMAPTNPC1MEN1KMT2A | |
| SCHEMBL6598860 | 0.70 | MEN1 (0.50) | TRPA1L3MBTL1RAB9AMAPTHPGD | |
| SCHEMBL29679102 | 0.70 | MEN1 (0.50) | TRPA1L3MBTL1RAB9AMAPTHPGD | |
| SCHEMBL6814044 | 0.68 | ALDH1A1 (0.38) | MAPTHPGDCYP2C9CYP2C19MEN1 | |
| SCHEMBL7067498 | 0.67 | MAPT (0.36) | L3MBTL1RAB9AMAPTHPGDNPC1 | |
| SCHEMBL12129028 | 0.66 | KDM4E (0.59) | L3MBTL1MAPTHPGDCYP2C19ALDH1A1 | |
| SCHEMBL166380 | 0.65 | NFE2L2 (0.61) | CYP2C9CYP2C19ALDH1A1POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040248739-A1 | Pyridylpropynyloxyphenyl derivatives for use as herbicides | SCHAETZER JURGEN (CH) | 2004-12-09 | — | — | US | disclosed |
| EP-1414301-A1 | PYRIDYLPROPYNYLOXYPHENYL DERIVATIVES FOR USE AS HERBICIDES | Syngenta Participations AG (CH) | 2004-05-06 | — | — | EP | disclosed |
| WO-2003013247-A1 | PYRIDYLPROPYNYLOXYPHENYL DERIVATIVES FOR USE AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2003-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248739-A1 | Pyridylpropynyloxyphenyl derivatives for use as herbicides | DDT, CYP4X1, CHRM1 | GRM5 667/4885TRPA1 736/4885L3MBTL1 2405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.