Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
| ▸ | ARG1 | P05089 | 1/20 | 0.30 |
| ▸ | ARG2 | P78540 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1806808 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL3615475 | 0.97 | — | — | |
| SCHEMBL1661228 | 0.88 | ALDH1A1 (0.33) | ALOX5 | |
| SCHEMBL8283396 | 0.88 | ALDH1A1 (0.33) | ALOX5 | |
| SCHEMBL21130778 | 0.88 | ALOX5 (0.31) | ALOX5 | |
| SCHEMBL23696015 | 0.88 | NOS3 (0.32) | ALOX5JAK2JAK1TYK2JAK3 | |
| SCHEMBL10266016 | 0.88 | ALDH1A1 (0.33) | ALOX5 | |
| SCHEMBL14470274 | 0.88 | NOS3 (0.32) | ALOX5JAK2JAK1TYK2JAK3 | |
| SCHEMBL2076710 | 0.87 | — | — | |
| SCHEMBL895491 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090215762-A1 | Siloxane polymer containing tethered levofloxacin | NDSU RESEARCH FOUNDATION | 2009-08-27 | — | — | US | claimed |
| US-20170097567-A1 | METHOD FOR PRODUCING POLYMER | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-04-06 | — | — | US | disclosed |
| US-20160229940-A1 | POLYMER, RESIST COMPOSITION, AND PATTERN FORMING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2016-08-11 | — | — | US | disclosed |
| US-8283432-B2 | Siloxane polymer containing tethered fluoroquinolone | NDSU RESEARCH FOUNDATION (US) | 2012-10-09 | — | — | US | disclosed |
| US-8278400-B2 | Antifouling materials containing cationic polysiloxanes | NDSU RESEARCH FOUNDATION (US) | 2012-10-02 | — | — | US | disclosed |
| US-20120046313-A1 | SILOXANE POLYMER CONTAINING TETHERED FLUOROQUINOLONE | NDSU RESEARCH FOUNDATION | 2012-02-23 | — | — | US | disclosed |
| US-20100204399-A1 | ANTIFOULING MATERIALS CONTAINING CATIONIC POLYSILOXANES | NDSU RESEARCH FOUNDATION | 2010-08-12 | — | — | US | disclosed |
| US-7771833-B2 | Anti-fouling materials containing cationic polysiloxanes | NDSU RESEARCH FOUNDATION (US) | 2010-08-10 | — | — | US | disclosed |
| US-20090215762-A1 | Siloxane polymer containing tethered levofloxacin | NDSU RESEARCH FOUNDATION | 2009-08-27 | — | — | US | disclosed |
| US-20070042199-A1 | Anti-fouling materials containing cationic polysiloxanes | NDSU RESEARCH FOUNDATION | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046313-A1 | SILOXANE POLYMER CONTAINING TETHERED FLUOROQUINOLONE | QARS1, SEPTIN7, SMCHD1 | ALOX5 2119/4885DAO 1748/4885SIGMAR1 786/4885 |
| US-20090215762-A1 | Siloxane polymer containing tethered levofloxacin | PUF60, QARS1, SEPTIN7 | ALOX5 1502/4885DAO 807/4885SIGMAR1 329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.