Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRF | P10586 | 8/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 8/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 8/20 | 0.37 |
| ▸ | GRN | P28799 | 1/20 | 0.34 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.31 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.31 |
| ▸ | PRNP | P04156 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6599382 | 0.91 | JAK2 (0.35) | PPARDALDH1A1POLBLMNARAB9A | |
| SCHEMBL6598856 | 0.85 | SMN1; SMN2 (0.43) | PTPRFPTPN2PTPN1GRNSORT1 | |
| SCHEMBL8316064 | 0.78 | FFAR1 (0.42) | PTPRFPTPN2PTPN1ALDH1A1POLB | |
| SCHEMBL6598831 | 0.77 | L3MBTL1 (0.37) | ALDH1A1POLBLMNARAB9A | |
| SCHEMBL8316517 | 0.76 | BCL2 (0.43) | ALDH1A1RAB9A | |
| SCHEMBL8553966 | 0.75 | JAK2 (0.36) | PTPRFPTPN2PTPN1ALDH1A1POLB | |
| SCHEMBL8315855 | 0.73 | RAB9A (0.48) | PTPRFPTPN2PTPN1ALDH1A1POLB | |
| SCHEMBL6598772 | 0.73 | TP53 (0.45) | PTPRFPTPN2PTPN1ALDH1A1POLB | |
| SCHEMBL3385454 | 0.72 | CYP26A1 (0.39) | PTPRFPTPN2PTPN1ALDH1A1POLB | |
| SCHEMBL8314166 | 0.69 | CA12 (0.41) | ALDH1A1HSD17B10CYP26A1CYP26B1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1170009-B1 | Thiazolybenzofuran derivatives and their use as SRS-A and leukotiene antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-04-07 | — | — | EP | disclosed |
| EP-1170009-A2 | Thiazolybenzofuran derivatives and their use as SRS-A and leukotiene antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-09 | — | — | EP | disclosed |
| US-5994378-A | ANTIALLERGENS; ANTIINFLAMMATORY AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-11-30 | — | — | US | disclosed |
| EP-0880519-A1 | THIAZOLYLBENZOFURAN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-12-02 | — | — | EP | disclosed |
| WO-1997027190-A1 | THIAZOLYLBENZOFURAN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-31 | — | — | WO | disclosed |