Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.54 |
| ▸ | ESR1 | P03372 | 4/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.50 |
| ▸ | LTA4H | P09960 | 3/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6595152 | 0.88 | LTA4H (0.55) | ESR1ESR2HRH3LTA4H | |
| SCHEMBL6594650 | 0.84 | LTA4H (0.60) | HRH3LTA4H | |
| SCHEMBL6593929 | 0.81 | ESR1 (0.56) | ESR1ESR2HRH3LTA4H | |
| SCHEMBL7774143 | 0.79 | LTA4H (0.55) | ESR1ESR2HRH3LTA4HCHEK1 | |
| SCHEMBL3968157 | 0.79 | AXL (0.58) | HRH3CHEK1 | |
| SCHEMBL7447133 | 0.78 | HRH3 (0.73) | ACHEHRH3LTA4HKDM4E | |
| SCHEMBL13032448 | 0.78 | JAK2 (0.65) | — | |
| SCHEMBL6595869 | 0.77 | ACHE (0.50) | ACHEESR1ESR2HRH3LTA4H | |
| SCHEMBL8337754 | 0.76 | HRH3 (0.70) | HRH3LTA4HKDM4E | |
| SCHEMBL7445580 | 0.76 | POLB (0.54) | ESR1ESR2HRH3LTA4HCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863755-B1 | ANTITHROMBOTIC DIAMINES | LILLY CO ELI (US) | 2004-12-15 | — | — | EP | disclosed |
| US-6265575-B1 | THROMBIN INHIBITORS | ELI LILLY AND COMPANY | 2001-07-24 | — | — | US | disclosed |
| US-6251921-B1 | ADMINISTERING THROMBIN INHIBITING DIAMINE COMPOUND TO MAMMAL | ELI LILLY AND COMPANY | 2001-06-26 | — | — | US | disclosed |
| US-6025382-A | Antithrombotic diamines | ELI LILLY AND COMPANY (US) | 2000-02-15 | — | — | US | disclosed |