Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.39 |
| ▸ | CTSL | P07711 | 9/20 | 0.39 |
| ▸ | CTSS | P25774 | 7/20 | 0.39 |
| ▸ | CTSB | P07858 | 6/20 | 0.39 |
| ▸ | CTSV | O60911 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CCR6 | P51684 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4685652 | 0.80 | CTSK (0.45) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6703554 | 0.79 | ALDH1A1 (0.44) | CTSKCTSLCTSSCTSBALDH1A1 | |
| SCHEMBL6697424 | 0.77 | CTSK (0.50) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6809592 | 0.77 | CTSK (0.50) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL7423583 | 0.73 | CTSK (0.42) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL5098825 | 0.73 | CTSK (0.43) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6590701 | 0.73 | CTSK (0.42) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL5105260 | 0.73 | CTSK (0.43) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6806158 | 0.72 | CTSL (0.49) | CTSKCTSLCTSSCTSB | |
| SCHEMBL6806160 | 0.72 | CTSL (0.49) | CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307204-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2004-06-02 | — | — | EP | disclosed |
| EP-1307204-A1 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2003-05-07 | — | — | EP | disclosed |
| WO-2001095911-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-12-20 | — | — | WO | disclosed |