Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4685652 | 0.87 | CTSK (0.45) | ALDH1A1CTSLCTSSCTSKCTSB | |
| SCHEMBL6703551 | 0.84 | ALDH1A1 (0.41) | ALDH1A1CTSLCTSSCTSKCTSB | |
| SCHEMBL6697424 | 0.83 | CTSK (0.50) | ALDH1A1CTSLCTSSCTSKCTSB | |
| SCHEMBL6809592 | 0.83 | CTSK (0.50) | ALDH1A1CTSLCTSSCTSKCTSB | |
| SCHEMBL7423583 | 0.81 | CTSK (0.42) | ALDH1A1GAACTSLCTSSCTSK | |
| SCHEMBL6590701 | 0.80 | CTSK (0.42) | ALDH1A1CTSLCTSSCTSKCTSB | |
| SCHEMBL6598086 | 0.79 | CTSK (0.39) | ALDH1A1CTSLCTSSCTSKCTSB | |
| SCHEMBL5098825 | 0.78 | CTSK (0.43) | CTSLCTSSCTSKCTSBLMNA | |
| SCHEMBL5096645 | 0.78 | CTSK (0.37) | ALDH1A1CTSLCTSSCTSKCTSB | |
| SCHEMBL5105260 | 0.78 | CTSK (0.43) | CTSLCTSSCTSKCTSBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040192674-A1 | Cathepsin L inhibitors | SMITHKLINE BEECHAM CORPORATION | 2004-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192674-A1 | Cathepsin L inhibitors | CTSE, CTSV, CTSL | ALDH1A1 3080/4885GAA 280/4885MEN1 4648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.