SCHEMBL65990

SCHEMBL65990

C=CCC(C[N+](C)(C)C)OP(=O)([O-])O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
CYP1A2 P05177 1/20 0.33
HRH1 P35367 1/20 0.33
CYP2C19 P33261 2/20 0.32
RECQL P46063 1/20 0.32
SLC25A20 O43772 3/20 0.31
TP53 P04637 2/20 0.31
CYP2D6 P10635 2/20 0.31
TSHR P16473 2/20 0.31
KDM4E B2RXH2 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPT P10636 1/20 0.31
CYP2C9 P11712 1/20 0.31
NFKB1 P19838 1/20 0.31
THPO P40225 1/20 0.31
HIF1A Q16665 1/20 0.31
HSD17B10 Q99714 1/20 0.31
SLC6A5 Q9Y345 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL170994 0.86 CYP1A2 (0.32) MEN1KMT2ACYP1A2HRH1CYP2C19
SCHEMBL3503898 0.85 MEN1 (0.34) MEN1KMT2ACYP1A2HRH1CYP2C19
SCHEMBL6469433 0.79 TDP1 (0.33)
SCHEMBL192296 0.79 MEN1 (0.39) MEN1KMT2ACYP1A2HRH1CYP2C19
SCHEMBL8468329 0.78 MEN1 (0.30) MEN1KMT2ACYP1A2HRH1
SCHEMBL1260630 0.77 MEN1 (0.33) MEN1KMT2ACYP1A2HRH1LMNA
SCHEMBL14739090 0.76 MEN1 (0.35) MEN1KMT2ACYP1A2HRH1CYP2C19
SCHEMBL1692410 0.76 MEN1 (0.37) MEN1KMT2ACYP1A2HRH1CYP2C19
SCHEMBL1260408 0.75 TSHR (0.37) MEN1KMT2ACYP1A2HRH1CYP2C19
SCHEMBL14739986 0.75 GABBR2 (0.36) MEN1KMT2ACYP1A2HRH1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1625 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122011871-A Biosensor polymer outer membrane and preparation method thereof 深圳希沃康医疗科技有限公司 2026-05-12 CN claimed
CN-117120020-A Implantable medical device for delivery of nucleic acid encapsulated particles 塞拉尼斯伊娃高性能聚合物公司 2023-11-24 CN claimed
US-20220389160-A1 EFFECTIVE INTRANASAL DELIVERY TO BRAIN INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) 2022-12-08 US claimed
CN-114641517-A Effective brain delivery technology by nasal administration 汉阳大学校产学协力团 2022-06-17 CN claimed
US-20220168325-A1 METHODS TO PROMOTE CEREBRAL BLOOD FLOW IN THE BRAIN THE UNIVERSITY OF VERMONT 2022-06-02 US claimed
US-11300572-B2 Methods and systems for producing nanolipoprotein particles LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) 2022-04-12 US claimed
US-20220096643-A1 Acryloyloxyethylphosphorylcholine Containing Polymer Conjugates And Their Preparation KODIAK SCIENCES INC (US) 2022-03-31 US claimed
US-10864169-B2 Conjugated polymer nanoparticles and manufacturing method thereof INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2020-12-15 US claimed
WO-2020198037-A1 METHODS TO PROMOTE CEREBRAL BLOOD FLOW IN THE BRAIN THE UNIVERSITY OF VERMONT (US) 2020-10-01 WO claimed
US-10752606-B2 Methods for treating protozoan infections NEOCULI PTY LTD. (AU) 2020-08-25 US claimed
US-20020090353-A1 Therapeutic modulation of the tumor inflammatory response IMUNAR CORPORATION 2002-07-11 US claimed
WO-2002030408-A2 COMPOSITIONS COMPRISING PHOSPHOLIPASE C INHIBITORS AND METHODS FOR ENHANCING PARACELLULAR PERMEABILITY ACROSS EPITHELIAL AND ENDOTHELIAL BARRIERS UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2002-04-18 WO claimed
US-6028209-A REACTING A FATTY ALCOHOL WITH PHOSPHORUS OXYCHLORIDE IN A SINGLE VESSEL PROCESS, THEN REACTING WITH CHOLINE SALT TO FORM PHOSPHORIC ACID DIESTER CHLORIDE, HYDROLYSIS AND ISOLATION ASTA MEDICA AG (DE) 2000-02-22 US claimed
US-5942639-A REACTING A C14-C18 N-ALKANOL WITH PHOSPHORUS OXYCHLORIDE THEN REACTING THE PRODUCT WITHOUT ISOLATION OR PURIFICATION WITH A CHOLINE SALT IN THE PRESENCE OF A BASE TO FORM THE PHOSPHORIC ACID DIESTER CHLORIDE, HYDROLYSING; MIXED BED ION EXCHANGING ASTA MEDICA AKTIENGESELLSCHAFT (DE) 1999-08-24 US claimed
EP-0858807-A2 Use of dopamine receptor antagonists in palliative tumor therapy ASTA Medica Aktiengesellschaft (DE) 1998-08-19 EP claimed
EP-0521297-B1 Process for the preparation of alkylphosphocholines and purification thereof ASTA MEDICA AG (DE) 1997-09-17 EP claimed
EP-0593897-B1 Stabilized solutions of alkylphosphocholine in glycerolalkylether ASTA MEDICA AG (DE) 1996-04-17 EP claimed
US-5446033-A Antitumor agent; storage stability, antiseptic, chemical resistance, by-product inhibition ASTA MEDICA AG (DE) 1995-08-29 US claimed
EP-0593897-A1 Stabilized solutions of alkylphosphocholine in glycerolalkylether ASTA Medica Aktiengesellschaft (DE) 1994-04-27 EP claimed
EP-0521297-A1 Process for the preparation of alkylphosphocholines and purification thereof ASTA Medica Aktiengesellschaft (DE) 1993-01-07 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220096643-A1 Acryloyloxyethylphosphorylcholine Containing Polymer Conjugates And Their Preparation PHOSPHO1, PCTP, SGMS1 MEN1 899/4885KMT2A 1288/4885CYP1A2 4247/4885
US-20220389160-A1 EFFECTIVE INTRANASAL DELIVERY TO BRAIN ADCYAP1R1, PCNP, CNP MEN1 279/4885KMT2A 3068/4885CYP1A2 1284/4885
US-10752606-B2 Methods for treating protozoan infections DPM1, ABCB11, PIGS MEN1 504/4885KMT2A 2912/4885CYP1A2 110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.