SCHEMBL6599043

SCHEMBL6599043

CCOC(=O)C(Cc1ccc2c(c1)c(C#N)cn2Cc1ccc2oc(-c3nc(C(C)(C)C)cs3)cc2c1)C(=O)OCC

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
XDH P47989 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6601989 0.86 XDH (0.34) XDH
SCHEMBL6622209 0.85 FFAR1 (0.40)
SCHEMBL6602878 0.85 PLA2G4A (0.39)
SCHEMBL6598454 0.84 XDH (0.33) XDH
SCHEMBL6598004 0.84 XDH (0.34) XDH
SCHEMBL6597700 0.84 MEN1 (0.34) XDH
SCHEMBL6598952 0.84 XDH (0.36) XDH
SCHEMBL8311230 0.84 CA12 (0.37)
SCHEMBL6599467 0.84 XDH (0.35) XDH
SCHEMBL6599799 0.83 XDH (0.38) XDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1170009-B1 Thiazolybenzofuran derivatives and their use as SRS-A and leukotiene antagonists FUJISAWA PHARMACEUTICAL CO (JP) 2004-04-07 EP disclosed
EP-1170009-A2 Thiazolybenzofuran derivatives and their use as SRS-A and leukotiene antagonists FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-01-09 EP disclosed
US-5994378-A ANTIALLERGENS; ANTIINFLAMMATORY AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1999-11-30 US disclosed