SCHEMBL6622209

SCHEMBL6622209

CC(C)(C)c1csc(-c2cc3cc(Cn4cc(C#N)c5cc(CCC(=O)O)ccc54)ccc3o2)n1

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 7/20 0.40
PLA2G4A P47712 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6602878 0.89 PLA2G4A (0.39) PLA2G4A
SCHEMBL6601989 0.89 XDH (0.34)
SCHEMBL6597700 0.88 MEN1 (0.34)
SCHEMBL6598004 0.88 XDH (0.34)
SCHEMBL6598454 0.88 XDH (0.33)
SCHEMBL14106844 0.86 XDH (0.35)
SCHEMBL6598952 0.86 XDH (0.36)
SCHEMBL6599043 0.85 XDH (0.34)
SCHEMBL6599799 0.85 XDH (0.38)
SCHEMBL6599467 0.84 XDH (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1170009-B1 Thiazolybenzofuran derivatives and their use as SRS-A and leukotiene antagonists FUJISAWA PHARMACEUTICAL CO (JP) 2004-04-07 EP disclosed
EP-1170009-A2 Thiazolybenzofuran derivatives and their use as SRS-A and leukotiene antagonists FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-01-09 EP disclosed
US-5994378-A ANTIALLERGENS; ANTIINFLAMMATORY AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1999-11-30 US disclosed