SCHEMBL65991

SCHEMBL65991

C=CCOP(=O)(O)OCC[N+](C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP3 P05413 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.37
ADRA1A P35348 2/20 0.37
LMNA P02545 2/20 0.37
ESR1 P03372 1/20 0.37
ADORA3 P0DMS8 1/20 0.37
CDC25A P30304 1/20 0.37
AGTR1 P30556 1/20 0.37
AKT1 P31749 1/20 0.37
KCNH2 Q12809 1/20 0.37
CHRM5 P08912 6/20 0.34
CHRM1 P11229 6/20 0.34
CHRM3 P20309 6/20 0.34
CHRM2 P08172 5/20 0.34
CHRM4 P08173 5/20 0.34
CHRNB2 P17787 4/20 0.34
CHRNA4 P43681 4/20 0.34
CHRNA7 P36544 3/20 0.34
BBOX1 O75936 2/20 0.34
HTR1A P08908 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25857265 0.84 SMN1; SMN2 (0.46) FABP3SMN1; SMN2ADRA1ALMNAESR1
SCHEMBL100728 0.84 FABP3 (0.39) FABP3SMN1; SMN2ADRA1ALMNAESR1
SCHEMBL29128926 0.83 LPAR3 (0.50) FABP3SMN1; SMN2ADRA1ALMNAESR1
SCHEMBL13619233 0.82 FABP3 (0.39) FABP3SMN1; SMN2ADRA1ALMNAESR1
SCHEMBL174096 0.80 BTN3A1 (0.40) SMN1; SMN2BTN3A1TSHRLPAR2LPAR3
SCHEMBL22568210 0.80 LPAR3 (0.60) FABP3ADRA1ALMNAESR1ADORA3
SCHEMBL4641076 0.79 LPAR3 (0.36) BTN3A1TSHRLPAR2LPAR3
SCHEMBL8598240 0.79 FABP3 (0.37) FABP3SMN1; SMN2ADRA1ALMNAESR1
SCHEMBL13745842 0.79 FABP3 (0.43) FABP3SMN1; SMN2ADRA1ALMNAESR1
SCHEMBL170993 0.79 LMNA (0.56) SMN1; SMN2ADRA1ALMNAESR1ADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1807 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4312951-A1 IMPLANTABLE MEDICAL DEVICE FOR THE DELIVERY OF NUCLEIC ACID-ENCAPSULATED PARTICLES Celanese EVA Performance Polymers LLC (US) 2024-02-07 EP claimed
CN-117120020-A Implantable medical device for delivery of nucleic acid encapsulated particles 塞拉尼斯伊娃高性能聚合物公司 2023-11-24 CN claimed
US-20220389160-A1 EFFECTIVE INTRANASAL DELIVERY TO BRAIN INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) 2022-12-08 US claimed
US-20220313616-A1 Implantable Medical Device for the Delivery of Nucleic Acid-Encapsulated Particles CELANESE EVA PERFORMANCE POLYMERS LLC 2022-10-06 US claimed
CN-114641517-A Effective brain delivery technology by nasal administration 汉阳大学校产学协力团 2022-06-17 CN claimed
US-20220168325-A1 METHODS TO PROMOTE CEREBRAL BLOOD FLOW IN THE BRAIN THE UNIVERSITY OF VERMONT 2022-06-02 US claimed
US-11300572-B2 Methods and systems for producing nanolipoprotein particles LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) 2022-04-12 US claimed
US-10864169-B2 Conjugated polymer nanoparticles and manufacturing method thereof INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2020-12-15 US claimed
WO-2020198037-A1 METHODS TO PROMOTE CEREBRAL BLOOD FLOW IN THE BRAIN THE UNIVERSITY OF VERMONT (US) 2020-10-01 WO claimed
US-10752606-B2 Methods for treating protozoan infections NEOCULI PTY LTD. (AU) 2020-08-25 US claimed
CN-1052878-C Stabilised hexadecylphosphocholine solutions in glycerol alkyl ethers ASTA MEDICAL AKTIENGESELLSCHAF (DE) 2000-05-31 CN claimed
US-6028209-A REACTING A FATTY ALCOHOL WITH PHOSPHORUS OXYCHLORIDE IN A SINGLE VESSEL PROCESS, THEN REACTING WITH CHOLINE SALT TO FORM PHOSPHORIC ACID DIESTER CHLORIDE, HYDROLYSIS AND ISOLATION ASTA MEDICA AG (DE) 2000-02-22 US claimed
US-5942639-A REACTING A C14-C18 N-ALKANOL WITH PHOSPHORUS OXYCHLORIDE THEN REACTING THE PRODUCT WITHOUT ISOLATION OR PURIFICATION WITH A CHOLINE SALT IN THE PRESENCE OF A BASE TO FORM THE PHOSPHORIC ACID DIESTER CHLORIDE, HYDROLYSING; MIXED BED ION EXCHANGING ASTA MEDICA AKTIENGESELLSCHAFT (DE) 1999-08-24 US claimed
EP-0858807-A2 Use of dopamine receptor antagonists in palliative tumor therapy ASTA Medica Aktiengesellschaft (DE) 1998-08-19 EP claimed
EP-0521297-B1 Process for the preparation of alkylphosphocholines and purification thereof ASTA MEDICA AG (DE) 1997-09-17 EP claimed
EP-0593897-B1 Stabilized solutions of alkylphosphocholine in glycerolalkylether ASTA MEDICA AG (DE) 1996-04-17 EP claimed
US-5446033-A Antitumor agent; storage stability, antiseptic, chemical resistance, by-product inhibition ASTA MEDICA AG (DE) 1995-08-29 US claimed
CN-1090174-A Stabilisation HEXADECYL PHOSPHOCHOLINE solution in the glycerol alkyl ether ASTA MEDICA AG (DE) 1994-08-03 CN claimed
EP-0593897-A1 Stabilized solutions of alkylphosphocholine in glycerolalkylether ASTA Medica Aktiengesellschaft (DE) 1994-04-27 EP claimed
EP-0521297-A1 Process for the preparation of alkylphosphocholines and purification thereof ASTA Medica Aktiengesellschaft (DE) 1993-01-07 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220389160-A1 EFFECTIVE INTRANASAL DELIVERY TO BRAIN ADCYAP1R1, PCNP, CNP FABP3 3792/4885SMN1; SMN2 271/4885ADRA1A 2766/4885
US-10752606-B2 Methods for treating protozoan infections DPM1, ABCB11, PIGS FABP3 4474/4885SMN1; SMN2 3002/4885ADRA1A 1852/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.